EYA4 anticorps (AA 153-224)

N° du produit ABIN7152365

Détail du produit anti-EYA4 anticorps

Antigène: EYA4 (Eyes Absent Homolog 4 (EYA4))

Épitope: AA 153-224

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EYA4 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Eyes absent homolog 4 protein (153-224AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:500-1:1000, IF:1:200-1:500,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur EYA4

Antigène: EYA4 (Eyes Absent Homolog 4 (EYA4))

Autre désignation: EYA4 (EYA4 Produits)

Synonymes: anticorps B130023L16Rik, anticorps CMD1J, anticorps DFNA10, anticorps EYA transcriptional coactivator and phosphatase 4, anticorps Eya4, anticorps EYA4

Sujet:

Background: Tyrosine phosphatase that specifically dephosphorylates \\\'Tyr-142\\\' of histone H2AX (H2AXY142ph). \\\'Tyr-142\\\' phosphorylation of histone H2AX plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress. Promotes efficient DNA repair by dephosphorylating H2AX, promoting the recruitment of DNA repair complexes containing MDC1. Its function as histone phosphatase probably explains its role in transcription regulation during organogenesis. May be involved in development of the eye (By similarity).

Aliases: CMD1J antibody, Deafness, autosomal dominant 10 antibody, DFNA 10 antibody, DFNA10 antibody, dJ78N10.1 (eyes absent (Drosophila) homolog 4) antibody, dJ78N10.1 (eyes absent) antibody, EYA 4 antibody, eya4 antibody, EYA4_HUMAN antibody, Eyes absent 4 antibody, Eyes absent homolog 4 (Drosophila) antibody, Eyes absent homolog 4 antibody, HGNC:3522 antibody, OTTHUMP00000040267 antibody

UniProt: O95677

Pathways: Sensory Perception of Sound