FBXO2 anticorps (AA 1-296)

N° du produit ABIN7152410

Détail du produit anti-FBXO2 anticorps

Antigène: FBXO2 (F-Box Protein 2 (FBXO2))

Épitope: AA 1-296

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FBXO2 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Réactivité croisée: Humain

Purification: Antigen Affinity Purified

Immunogène: Recombinant Human F-box only protein 2 protein (1-296AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur FBXO2

Antigène: FBXO2 (F-Box Protein 2 (FBXO2))

Autre désignation: FBXO2 (FBXO2 Produits)

Synonymes: anticorps FBG1, anticorps FBX2, anticorps Fbs1, anticorps NFB42, anticorps OCP1, anticorps Fbs2, anticorps Prpl4, anticorps F-box protein 2, anticorps FBXO2, anticorps Fbxo2

Sujet:

Background: Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Involved in the endoplasmic reticulum-associated degradation pathway (ERAD) for misfolded lumenal proteins by recognizing and binding sugar chains on unfolded glycoproteins that are retrotranslocated into the cytosol and promoting their ubiquitination and subsequent degradation. Prevents formation of cytosolic aggregates of unfolded glycoproteins that have been retrotranslocated into the cytosol. Able to recognize and bind denatured glycoproteins, preferentially those of the high-mannose type (By similarity).

Aliases: F box gene 1 antibody, F box only protein 2 antibody, F box protein 2 antibody, F box protein only 2 antibody, F-box only protein 2 antibody, FBG 1 antibody, FBG1 antibody, Fbs 1 antibody, Fbs1 antibody, Fbs2 antibody, FBX 2 antibody, FBX2 antibody, FBX2_HUMAN antibody, FBXO 2 antibody, FBXO2 antibody, Neural F box protein NFB42 antibody, Neural F-box protein, 42-KD, rat, homolog of antibody, NFB 42 antibody, NFB42 antibody, OCP1 antibody, organ of Corti protein 1 antibody, Prpl4 antibody

UniProt: Q9UK22