F-Box Protein 3 anticorps (AA 276-376)

N° du produit ABIN7152425

Détail du produit anti-F-Box Protein 3 anticorps

Antigène: F-Box Protein 3 (FBXO3)

Épitope: AA 276-376

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp F-Box Protein 3 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Réactivité croisée: Humain, Souris

Purification: >95%, Protein G purified

Immunogène: Recombinant Human F-box only protein 3 protein (276-376AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:200-1:5000, IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur F-Box Protein 3

Antigène: F-Box Protein 3 (FBXO3)

Autre désignation: FBXO3 (FBXO3 Produits)

Synonymes: anticorps FBA, anticorps FBX3, anticorps 1200002G09Rik, anticorps 1700026K02Rik, anticorps AI046358, anticorps Fba, anticorps zgc:112485, anticorps DKFZp459H187, anticorps F-box protein 3, anticorps F-box protein 3 S homeolog, anticorps FBXO3, anticorps Fbxo3, anticorps fbxo3.S, anticorps fbxo3

Sujet:

Background: Substrate recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Mediates the ubiquitination of HIPK2 and probably that of EP300, leading to rapid degradation by the proteasome. In the presence of PML, HIPK2 ubiquitination still occurs, but degradation is prevented. PML, HIPK2 and FBXO3 may act synergically to activate p53/TP53-dependent transactivation.

Aliases: F Box G - Domain 3 antibody, F box only protein 3 antibody, F box protein 3 antibody, F box protein FBX3 antibody, F-box only protein 3 antibody, FBA antibody, FBX3 antibody, FBX3_HUMAN antibody, FBXO3 antibody

UniProt: Q9UK99