FBXO9 anticorps (AA 13-111)
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- Antigène Voir toutes FBXO9 Anticorps
- FBXO9 (F-Box Protein 9 (FBXO9))
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Épitope
- AA 13-111
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp FBXO9 est non-conjugé
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Application
- ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- Réactivité croisée
- Humain
- Purification
- >95%, Protein G purified
- Immunogène
- Recombinant Human F-box only protein 9 protein (13-111AA)
- Isotype
- IgG
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anti-F-Box Protein 9 (FBXO9) (AA 338-447) antibody
FBXO9 Reactivité: Humain ELISA, IHC (p) Hôte: Souris Monoclonal 1G12 unconjugated
anti-F-Box Protein 9 (FBXO9) (AA 1-437) antibodyFBXO9 Reactivité: Humain WB, IF Hôte: Souris Polyclonal unconjugated
anti-F-Box Protein 9 (FBXO9) (Middle Region) antibodyFBXO9 Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Poisson zèbre (Danio rerio), Cheval, Porc, Lapin, Cobaye, Saccharomyces cerevisiae WB, IHC Hôte: Lapin Polyclonal unconjugated
anti-F-Box Protein 9 (FBXO9) antibodyFBXO9 Reactivité: Humain, Souris, Rat WB, ELISA Hôte: Lapin Polyclonal unconjugated
anti-F-Box Protein 9 (FBXO9) (AA 346-373), (C-Term) antibodyFBXO9 Reactivité: Humain, Souris WB Hôte: Lapin Polyclonal RB26852 unconjugated
anti-F-Box Protein 9 (FBXO9) (AA 431-447) antibodyFBXO9 Reactivité: Humain WB, ELISA Hôte: Lapin Polyclonal unconjugated
anti-F-Box Protein 9 (FBXO9) (AA 179-228) antibodyFBXO9 Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Poulet, Cheval, Porc, Lapin, Roussette (Chauve-souris) WB, IHC, IHC (p) Hôte: Lapin Polyclonal unconjugated
anti-F-Box Protein 9 (FBXO9) (AA 346-373), (C-Term) antibodyFBXO9 Reactivité: Humain, Souris WB, FACS Hôte: Lapin Polyclonal unconjugated
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- Indications d'application
- Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Antigène
- FBXO9 (F-Box Protein 9 (FBXO9))
- Autre désignation
- FBXO9 (FBXO9 Produits)
- Synonymes
- anticorps fbxo9, anticorps MGC75727, anticorps FBXO9, anticorps fbx9, anticorps FBX9, anticorps NY-REN-57, anticorps VCIA1, anticorps dJ341E18.2, anticorps wu:fc79g12, anticorps zgc:56212, anticorps zgc:77654, anticorps 9030401P18Rik, anticorps AA986398, anticorps F-box protein 9, anticorps F-box only protein 9, anticorps f-box protein 9, anticorps F-box protein 9 L homeolog, anticorps fbxo9, anticorps FBXO9, anticorps CpipJ_CPIJ012920, anticorps Tsp_03945, anticorps fbx9, anticorps Fbxo9, anticorps fbxo9.L
- Sujet
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Background: Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of TTI1 and TELO2 in a CK2-dependent manner, thereby directly regulating mTOR signaling. SCF(FBXO9) recognizes and binds mTORC1-bound TTI1 and TELO2 when they are phosphorylated by CK2 following growth factor deprivation, leading to their degradation. In contrast, the SCF(FBXO9) does not mediate ubiquitination of TTI1 and TELO2 when they are part of the mTORC2 complex. As a consequence, mTORC1 is inactivated to restrain cell growth and protein translation, while mTORC2 is activated due to the relief of feedback inhibition by mTORC1.
Aliases: Cross-immune reaction antigen 1 antibody, dJ341E18.2 antibody, DKFZp434C0118 antibody, F-box only protein 9 antibody, Fbp24 antibody, FBX09 antibody, FBX9 antibody, FBX9_HUMAN antibody, Fbxo9 antibody, KIAA0936 antibody, NY REN 57 antibody, OTTHUMP00000016628 antibody, OTTHUMP00000016629 antibody, OTTHUMP00000214588 antibody, Renal carcinoma antigen NY-REN-57 antibody, VCIA1 antibody
- UniProt
- Q9UK97
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