FCRL3 anticorps (AA 122-222)
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- Antigène Voir toutes FCRL3 Anticorps
- FCRL3 (Fc Receptor-Like 3 (FCRL3))
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Épitope
- AA 122-222
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp FCRL3 est non-conjugé
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Application
- Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
- Réactivité croisée
- Humain
- Purification
- >95%, Protein G purified
- Immunogène
- Recombinant Human Fc receptor-like protein 3 protein (122-222AA)
- Isotype
- IgG
- Top Product
- Discover our top product FCRL3 Anticorps primaire
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- Indications d'application
- Recommended dilution: IHC:1:20-1:200, IF:1:20-1:200,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Antigène
- FCRL3 (Fc Receptor-Like 3 (FCRL3))
- Autre désignation
- FCRL3 (FCRL3 Produits)
- Synonymes
- anticorps CD307c, anticorps FCRH3, anticorps IFGP3, anticorps IRTA3, anticorps SPAP2, anticorps fcrh3, anticorps ifgp3, anticorps irta3, anticorps spap2, anticorps xfl1.2, anticorps Fc receptor like 3, anticorps Fc receptor-like 3 L homeolog, anticorps Fc receptor-like 3, anticorps Fc receptor-like 3 S homeolog, anticorps FCRL3, anticorps fcrl3.L, anticorps fcrl3, anticorps fcrl3.S
- Sujet
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Background: Promotes TLR9-induced B-cell proliferation, activation and survival but inhibits antibody production and suppresses plasma cell differentiation. Enhances activation of NF-kappa-B and MAPK signaling pathways in TLR9 stimulated B-cells (PubMed:23857366). Has inhibitory potentional on B-cell receptor (BCR)-mediated signaling, possibly through association with SH2 domain-containing phosphatases. Inhibits cell tyrosine phosphorylation, calcium mobilization and activation-induced cell death induced through BCR signaling (PubMed:19843936). Regulatory T-cells expressing FCRL3 exhibit a memory phenotype, are relatively nonresponsive to antigenic stimulation in presence of IL2 and have reduced capacity to suppress the proliferation of effector T-cells (PubMed:20190142, PubMed:19494275).
Aliases: CD307c antibody, Fc receptor homolog 3 antibody, Fc receptor-like protein 3 antibody, FcR-like protein 3 antibody, FcRH3 antibody, FcRL3 antibody, FCRL3_HUMAN antibody, hIFGP3 antibody, IFGP family protein 3 antibody, IFGP3 antibody, Immune receptor translocation-associated protein 3 antibody, Immunoglobulin superfamily receptor translocation associated protein 3 antibody, IRTA3 antibody, SH2 domain-containing phosphatase anchor protein 2 antibody, SPAP2 antibody
- UniProt
- Q96P31
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