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FCRL3 anticorps (AA 122-222) (Biotin)

FCRL3 Reactivité: Humain ELISA Hôte: Lapin Polyclonal Biotin
N° du produit ABIN7152659
  • Antigène Voir toutes FCRL3 Anticorps
    FCRL3 (Fc Receptor-Like 3 (FCRL3))
    Épitope
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 122-222
    Reactivité
    • 11
    • 1
    • 1
    Humain
    Hôte
    • 7
    • 4
    Lapin
    Clonalité
    • 7
    • 4
    Polyclonal
    Conjugué
    • 8
    • 1
    • 1
    • 1
    Cet anticorp FCRL3 est conjugé à/à la Biotin
    Application
    • 5
    • 4
    • 4
    • 3
    • 1
    ELISA
     Réactivité croisée
    Humain
    Purification
    >95%, Protein G purified
    Immunogène
    Recombinant Human Fc receptor-like protein 3 protein (122-222AA)
    Isotype
    IgG
    Top Product
    Discover our top product FCRL3 Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Antigène
    FCRL3 (Fc Receptor-Like 3 (FCRL3))
    Autre désignation
    FCRL3 (FCRL3 Produits)
    Sujet

    Background: Promotes TLR9-induced B-cell proliferation, activation and survival but inhibits antibody production and suppresses plasma cell differentiation. Enhances activation of NF-kappa-B and MAPK signaling pathways in TLR9 stimulated B-cells (PubMed:23857366). Has inhibitory potentional on B-cell receptor (BCR)-mediated signaling, possibly through association with SH2 domain-containing phosphatases. Inhibits cell tyrosine phosphorylation, calcium mobilization and activation-induced cell death induced through BCR signaling (PubMed:19843936). Regulatory T-cells expressing FCRL3 exhibit a memory phenotype, are relatively nonresponsive to antigenic stimulation in presence of IL2 and have reduced capacity to suppress the proliferation of effector T-cells (PubMed:20190142, PubMed:19494275).

    Aliases: CD307c antibody, Fc receptor homolog 3 antibody, Fc receptor-like protein 3 antibody, FcR-like protein 3 antibody, FcRH3 antibody, FcRL3 antibody, FCRL3_HUMAN antibody, hIFGP3 antibody, IFGP family protein 3 antibody, IFGP3 antibody, Immune receptor translocation-associated protein 3 antibody, Immunoglobulin superfamily receptor translocation associated protein 3 antibody, IRTA3 antibody, SH2 domain-containing phosphatase anchor protein 2 antibody, SPAP2 antibody

    UniProt
    Q96P31
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