FERMT2 anticorps (AA 155-232)

N° du produit ABIN7152702

Détail du produit anti-FERMT2 anticorps

Antigène: FERMT2 (Fermitin Family Member 2 (FERMT2))

Épitope: AA 155-232

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FERMT2 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Fermitin family homolog 2 protein (155-232AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:500-1:1000, IF:1:50-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur FERMT2

Antigène: FERMT2 (Fermitin Family Member 2 (FERMT2))

Autre désignation: FERMT2 (FERMT2 Produits)

Synonymes: anticorps AA960555, anticorps Kindlin-2, anticorps Mig2, anticorps Plekhc1, anticorps KIND2, anticorps MIG2, anticorps PLEKHC1, anticorps UNC112, anticorps UNC112B, anticorps mig-2, anticorps fermitin family member 2, anticorps Fermt2, anticorps FERMT2

Sujet:

Background: Scaffolding protein that enhances integrin activation mediated by TLN1 and/or TLN2, but activates integrins only weakly by itself. Binds to membranes enriched in phosphoinositides. Enhances integrin-mediated cell adhesion onto the extracellular matrix and cell spreading, this requires both its ability to interact with integrins and with phospholipid membranes. Required for the assembly of focal adhesions. Participates in the connection between extracellular matrix adhesion sites and the actin cytoskeleton and also in the orchestration of actin assembly and cell shape modulation. Recruits FBLIM1 to focal adhesions. Plays a role in the TGFB1 and integrin signaling pathways. Stabilizes active CTNNB1 and plays a role in the regulation of transcription mediated by CTNNB1 and TCF7L2/TCF4 and in Wnt signaling.

Aliases: FLJ34213 antibody, FLJ44462 antibody, UNC112 antibody, FERM2_HUMAN antibody, Fermitin family homolog 2 antibody, Fermt2 antibody, KIND2 antibody, Kindlin-2 antibody, MIG-2 antibody, MIG2 antibody, Mitogen-inducible gene 2 protein antibody, PH domain-containing family C member 1 antibody, Pleckstrin homology domain containing family C (with FERM domain) member 1 antibody, Pleckstrin homology domain-containing family C member 1 antibody, PLEKHC1 antibody, UNC112B antibody

UniProt: Q96AC1

Pathways: Cell-Cell Junction Organization