FGG anticorps (AA 278-437)

N° du produit ABIN7152763

Détail du produit anti-FGG anticorps

Antigène: FGG (Fibrinogen gamma Chain (FGG))

Épitope: AA 278-437

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FGG est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Réactivité croisée: Humain, Souris

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Fibrinogen gamma chain protein (278-437AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:200-1:5000, IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur FGG

Antigène: FGG (Fibrinogen gamma Chain (FGG))

Autre désignation: FGG (FGG Produits)

Synonymes: anticorps FXII, anticorps HAF, anticorps 3010002H13Rik, anticorps AI256424, anticorps fibrinogen, anticorps FGG, anticorps LOC100220680, anticorps fb60h05, anticorps fb62e01, anticorps wu:fb60h05, anticorps wu:fb62e01, anticorps zgc:56023, anticorps fibrinogen gamma chain, anticorps coagulation factor XII (Hageman factor), anticorps fibrinogen gamma chain L homeolog, anticorps FGG, anticorps F12, anticorps fgg, anticorps Fgg, anticorps fgg.L, anticorps CpipJ_CPIJ006387, anticorps CpipJ_CPIJ010087

Sujet:

Background: Together with fibrinogen alpha (FGA) and fibrinogen beta (FGB), polymerizes to form an insoluble fibrin matrix. Has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However, subsequent studies have shown that it is not absolutely required for thrombus formation in vivo. Enhances expression of SELP in activated platelets via an ITGB3-dependent pathway. Maternal fibrinogen is essential for successful pregnancy. Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage. May also facilitate the antibacterial immune response via both innate and T-cell mediated pathways.

Aliases: FGG antibody, FIBG_HUMAN antibody, Fibrinogen gamma chain antibody, Fibrinogen gamma polypeptide antibody, fibrinogen gamma-b chain antibody

UniProt: P02679