FZD9 anticorps (AA 23-229)

N° du produit ABIN7153197

Détail du produit anti-FZD9 anticorps

Antigène: FZD9 (Frizzled Family Receptor 9 (FZD9))

Épitope: AA 23-229

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FZD9 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Réactivité croisée: Humain, Souris

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Frizzled-9 protein (23-229AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:500-1:5000, IHC:1:500-1:1000,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur FZD9

Antigène: FZD9 (Frizzled Family Receptor 9 (FZD9))

Autre désignation: FZD9 (FZD9 Produits)

Synonymes: anticorps CD349, anticorps FZD3, anticorps mfz9, anticorps Fz-9, anticorps cFz-9, anticorps fz11, anticorps fzd9, anticorps fzx, anticorps hm:zehl0603, anticorps zehl0603, anticorps zg11, anticorps frizzled class receptor 9, anticorps frizzled class receptor 9a, anticorps frizzled class receptor 9b, anticorps FZD9, anticorps Fzd9, anticorps fzd9a, anticorps fzd9b

Sujet:

Background: Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues.

Aliases: CD 349 antibody, CD 349 antigen antibody, CD349 antibody, Frizzled Drosophila homolog of 3 antibody, Frizzled homolog 9 (Drosophila) antibody, Frizzled homolog 9 antibody, Frizzled-9 antibody, Fz 9 antibody, Fz-9 antibody, FZD 3 antibody, Fzd 9 antibody, FZD3 antibody, FZD3-PEN antibody, FZD9 antibody, FZD9_HUMAN antibody, FzE6 antibody, hFz9 antibody, mfz9 antibody, Xfz9 antibody

UniProt: O00144

Pathways: Signalisation WNT