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Mare/Nprl3/C16orf35 anticorps (AA 349-482)

C16orf35 Reactivité: Humain WB, ELISA, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7153701
  • Antigène Voir toutes Mare/Nprl3/C16orf35 (C16orf35) Anticorps
    Mare/Nprl3/C16orf35 (C16orf35) (MARE (C16orf35))
    Épitope
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    AA 349-482
    Reactivité
    • 10
    • 1
    Humain
    Hôte
    • 5
    • 4
    • 1
    Lapin
    Clonalité
    • 7
    • 3
    Polyclonal
    Conjugué
    • 7
    • 1
    • 1
    • 1
    Cet anticorp Mare/Nprl3/C16orf35 est non-conjugé
    Application
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
     Réactivité croisée
    Humain
    Purification
    >95%, Protein G purified
    Immunogène
    Recombinant Human GATOR complex protein NPRL3 protein (349-482AA)
    Isotype
    IgG
  • Indications d'application
    Recommended dilution: WB:1:500-1:5000, IHC:1:200-1:500,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Antigène
    Mare/Nprl3/C16orf35 (C16orf35) (MARE (C16orf35))
    Autre désignation
    NPRL3 (C16orf35 Produits)
    Synonymes
    anticorps C16orf35, anticorps CGTHBA, anticorps HS-40, anticorps MARE, anticorps NPR3, anticorps RMD11, anticorps Aag, anticorps HS-26, anticorps Mare, anticorps Phg, anticorps Prox1, anticorps m(alpha)RE, anticorps RGD1308665, anticorps c16orf35, anticorps cgthba, anticorps hs-40, anticorps mare, anticorps npr3, anticorps nprl3, anticorps rmd11, anticorps NPR3 like, GATOR1 complex subunit, anticorps nitrogen permease regulator-like 3, anticorps NPR3-like, GATOR1 complex subunit, anticorps NPR3-like, GATOR1 complex subunit L homeolog, anticorps NPRL3, anticorps Nprl3, anticorps nprl3.L
    Sujet

    Background: As a component of the GATOR1 complex functions as an inhibitor of the amino acid-sensing branch of the TORC1 pathway. The GATOR1 complex strongly increases GTP hydrolysis by RRAGA and RRAGB within RRAGC-containing heterodimers, thereby deactivating RRAGs, releasing mTORC1 from lysosomal surface and inhibiting mTORC1 signaling. The GATOR1 complex is negatively regulated by GATOR2 the other GATOR subcomplex in this amino acid-sensing branch of the TORC1 pathway.

    Aliases: otein antibody, Alpha-globin regulatory element-containing gene protein antibody, C16ORF35 antibody, CGTHBA antibody, Conserved gene telomeric to alpha globin cluster antibody, HS 40 antibody, MARE antibody, Nitrogen permease regulator 3-like protein antibody, Nitrogen permease regulator-like 3 (S. cerevisiae) antibody, NPR3 antibody, NPRL3 antibody, NPRL3_HUMAN antibody, Protein CGTHBA antibody, RMD11 antibody

    UniProt
    Q12980
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