WDR24 anticorps (AA 1-298)

N° du produit ABIN7153705

Détail du produit anti-WDR24 anticorps

Antigène: WDR24 (WD Repeat Domain 24 (WDR24))

Épitope: AA 1-298

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp WDR24 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human GATOR complex protein WDR24 protein (1-298AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:200-1:500,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur WDR24

Antigène: WDR24 (WD Repeat Domain 24 (WDR24))

Autre désignation: WDR24 (WDR24 Produits)

Synonymes: anticorps C16orf21, anticorps JFP7, anticorps BC037651, anticorps wu:fd05f12, anticorps zgc:55946, anticorps WD repeat domain 24, anticorps WD repeat domain 24 L homeolog, anticorps WDR24, anticorps Wdr24, anticorps wdr24, anticorps wdr24.L

Sujet:

Background: As a component of the GATOR subcomplex GATOR2, functions within the amino acid-sensing branch of the TORC1 signaling pathway (PubMed:23723238, PubMed:27166823). Indirectly activates mTORC1 and the TORC1 signaling pathway through the inhibition of the GATOR1 subcomplex (PubMed:23723238). It is negatively regulated by the upstream amino acid sensors SESN2 and CASTOR1 (PubMed:26449471, PubMed:26586190, PubMed:27487210). In addition to its role in regulation of the TORC1 complex, promotes the acidification of lysosomes and facilitates autophagic flux (PubMed:27166823).

Aliases: C16orf21 antibody, DKFZp434F054 antibody, JFP7 antibody, LA16c-313D11.2 antibody, WD repeat-containing protein 24 antibody, wdr24 antibody, WDR24_HUMAN antibody

UniProt: Q96S15