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WDR59 anticorps (AA 619-862)

WDR59 Reactivité: Humain WB, ELISA, IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7153709
  • Antigène Tous les produits WDR59
    WDR59 (WD Repeat Domain 59 (WDR59))
    Épitope
    • 3
    • 1
    • 1
    • 1
    • 1
    AA 619-862
    Reactivité
    • 7
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    Humain
    Hôte
    • 8
    Lapin
    Clonalité
    • 8
    Polyclonal
    Conjugué
    • 5
    • 1
    • 1
    • 1
    Cet anticorp WDR59 est non-conjugé
    Application
    Western Blotting (WB), ELISA, Immunofluorescence (IF)
     Réactivité croisée
    Humain
    Purification
    >95%, Protein G purified
    Immunogène
    Recombinant Human GATOR complex protein WDR59 protein (619-862AA)
    Isotype
    IgG
  • Indications d'application
    Recommended dilution: WB:1:1000-1:5000, IF:1:50-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Antigène
    WDR59 (WD Repeat Domain 59 (WDR59))
    Autre désignation
    WDR59 (WDR59 Produits)
    Synonymes
    anticorps 5430401O09Rik, anticorps Cdw12, anticorps WD repeat domain 59, anticorps WDR59, anticorps Wdr59
    Sujet

    Background: As a component of the GATOR subcomplex GATOR2, functions within the amino acid-sensing branch of the TORC1 signaling pathway. Indirectly activates mTORC1 and the TORC1 signaling pathway through the inhibition of the GATOR1 subcomplex (PubMed:23723238). It is negatively regulated by the upstream amino acid sensors SESN2 and CASTOR1 (PubMed:25457612, PubMed:27487210).

    Aliases: WDR59 antibody, KIAA1923 antibody, FP977 antibody, GATOR complex protein WDR59 antibody, WD repeat-containing protein 59 antibody

    UniProt
    Q6PJI9
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