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GEMIN4 anticorps (AA 741-848) (Biotin)

GEMIN4 Reactivité: Humain ELISA Hôte: Lapin Polyclonal Biotin
N° du produit ABIN7153758
  • Antigène Voir toutes GEMIN4 Anticorps
    GEMIN4 (Gem (Nuclear Organelle) Associated Protein 4 (GEMIN4))
    Épitope
    • 15
    • 14
    • 8
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    AA 741-848
    Reactivité
    • 50
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 46
    • 4
    Lapin
    Clonalité
    • 47
    • 3
    Polyclonal
    Conjugué
    • 17
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp GEMIN4 est conjugé à/à la Biotin
    Application
    • 38
    • 23
    • 13
    • 13
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    ELISA
     Réactivité croisée
    Humain
    Purification
    >95%, Protein G purified
    Immunogène
    Recombinant Human Gem-associated protein 4 protein (741-848AA)
    Isotype
    IgG
    Top Product
    Discover our top product GEMIN4 Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Antigène
    GEMIN4 (Gem (Nuclear Organelle) Associated Protein 4 (GEMIN4))
    Autre désignation
    GEMIN4 (GEMIN4 Produits)
    Synonymes
    anticorps HC56, anticorps HCAP1, anticorps HHRF-1, anticorps p97, anticorps 4932415L08Rik, anticorps AU015359, anticorps im:7143815, anticorps wu:fc41c09, anticorps zgc:110169, anticorps GEMIN4, anticorps RGD1563715, anticorps gem nuclear organelle associated protein 4, anticorps gem (nuclear organelle) associated protein 4, anticorps GEMIN4, anticorps Gemin4, anticorps gemin4
    Sujet

    Background: The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chaperone CLNS1A that controls the assembly of the core snRNP. Dissociation by the SMN complex of CLNS1A from the trapped Sm proteins and their transfer to an SMN-Sm complex triggers the assembly of core snRNPs and their transport to the nucleus.

    Aliases: GEMIN4 antibody, Gem-associated protein 4 antibody, Gemin-4 antibody, Component of gems 4 antibody, p97 antibody

    UniProt
    P57678
    Pathways
    Ribonucleoprotein Complex Subunit Organization
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