GEMIN6 anticorps (AA 1-167)

N° du produit ABIN7153761

Détail du produit anti-GEMIN6 anticorps

Antigène: GEMIN6 (Gem (Nuclear Organelle) Associated Protein 6 (GEMIN6))

Épitope: AA 1-167

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GEMIN6 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Gem-associated protein 6 protein (1-167AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur GEMIN6

Antigène: GEMIN6 (Gem (Nuclear Organelle) Associated Protein 6 (GEMIN6))

Autre désignation: GEMIN6 (GEMIN6 Produits)

Synonymes: anticorps 2610019B15Rik, anticorps 2810470M17Rik, anticorps gemin6, anticorps gem nuclear organelle associated protein 6, anticorps gem (nuclear organelle) associated protein 6, anticorps gem nuclear organelle associated protein 6 S homeolog, anticorps GEMIN6, anticorps Gemin6, anticorps gemin6.S

Sujet:

Background: The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chaperone CLNS1A that controls the assembly of the core snRNP. Dissociation by the SMN complex of CLNS1A from the trapped Sm proteins and their transfer to an SMN-Sm complex triggers the assembly of core snRNPs and their transport to the nucleus.

Aliases: FLJ23459 antibody, Gem (nuclear organelle) associated protein 6 antibody, Gem-associated protein 6 antibody, GEMI6 antibody, GEMI6_HUMAN antibody, Gemin 6 antibody, Gemin-6 antibody, Gemin6 antibody, SIP2 antibody

UniProt: Q8WXD5

Pathways: Ribonucleoprotein Complex Subunit Organization