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GRHL3 anticorps (AA 31-182) (HRP)

GRHL3 Reactivité: Humain ELISA Hôte: Lapin Polyclonal HRP
N° du produit ABIN7154383
  • Antigène Voir toutes GRHL3 Anticorps
    GRHL3 (Grainyhead-Like 3 (GRHL3))
    Épitope
    • 15
    • 9
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 31-182
    Reactivité
    • 34
    • 10
    • 6
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 1
    Humain
    Hôte
    • 32
    • 2
    Lapin
    Clonalité
    • 32
    • 2
    Polyclonal
    Conjugué
    • 21
    • 4
    • 3
    • 2
    • 2
    • 2
    Cet anticorp GRHL3 est conjugé à/à la HRP
    Application
    • 27
    • 20
    • 7
    • 2
    • 1
    • 1
    • 1
    • 1
    ELISA
     Réactivité croisée
    Humain
    Purification
    >95%, Protein G purified
    Immunogène
    Recombinant Human Grainyhead-like protein 3 homolog protein (31-182AA)
    Isotype
    IgG
    Top Product
    Discover our top product GRHL3 Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Antigène
    GRHL3 (Grainyhead-Like 3 (GRHL3))
    Autre désignation
    GRHL3 (GRHL3 Produits)
    Synonymes
    anticorps GRHL3, anticorps SOM, anticorps TFCP2L4, anticorps AI561912, anticorps Get1, anticorps Som, anticorps Tfcp2l4, anticorps ct, anticorps grainyhead like transcription factor 3, anticorps grainyhead-like 3 (Drosophila), anticorps grainyhead-like transcription factor 3, anticorps GRHL3, anticorps Grhl3
    Sujet

    Background: Transcription factor playing important roles in primary neurulation and in the differentiation of stratified epithelia of both ectodermal and endodermal origin (By similarity). Binds directly to the consensus DNA sequence 5\'-AACCGGTT-3\' acting as an activator and repressor on distinct target genes (PubMed:21081122, PubMed:25347468). xhibits functional redundancy with GRHL2 in epidermal morphogenetic events and epidermal wound repair (By similarity). Exhibits functional redundancy with GRHL2 in epidermal morphogenetic events and epidermal wound repair but is essential to form the epidermal barrier with TGM3 as critical direct target gene among others. Despite being dispensable during normal epidermal homeostasis in the adulthood, is again required for barrier repair after immune-mediated epidermal damage, regulates distinct gene batteries in embryonic epidermal differentiation and adult epidermal barrier reformation after injury. Plays unique and cooperative roles with GRHL2 in establishing distinct zones of primary neurulation. Essential for spinal closure, functions cooperatively with GRHL2 in closure 2 (forebrain/midbrain boundary) and posterior neuropore closure (By similarity). Also required for proper development of the oral periderm (PubMed:24360809). No genetic interaction with GRHL3, no functional cooperativity due to diverse target gene selectivity (PubMed:21081122).

    Aliases: Drosophila antibody, Grainyhead like 3 antibody, Grainyhead like protein 3 homolog antibody, Grainyhead-like protein 3 homolog antibody, grhl3 antibody, GRHL3_HUMAN antibody, Sister of mammalian grainyhead antibody, Sister of mammalian grainyhead protein antibody, SOM antibody, TFCP2L4 antibody, Transcription factor CP2 like 4 antibody, Transcription factor CP2-like 4 antibody

    UniProt
    Q8TE85
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