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GRB14 anticorps (AA 294-397)

GRB14 Reactivité: Humain ELISA, IHC, IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7154498
  • Antigène Voir toutes GRB14 Anticorps
    GRB14 (Growth Factor Receptor-Bound Protein 14 (GRB14))
    Épitope
    • 15
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 294-397
    Reactivité
    • 31
    • 8
    • 7
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 31
    Lapin
    Clonalité
    • 31
    Polyclonal
    Conjugué
    • 13
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp GRB14 est non-conjugé
    Application
    • 13
    • 13
    • 12
    • 11
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
     Réactivité croisée
    Humain
    Purification
    >95%, Protein G purified
    Immunogène
    Recombinant Human Growth factor receptor-bound protein 14 protein (294-397AA)
    Isotype
    IgG
  • Indications d'application
    Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Antigène
    GRB14 (Growth Factor Receptor-Bound Protein 14 (GRB14))
    Autre désignation
    GRB14 (GRB14 Produits)
    Synonymes
    anticorps GRB14, anticorps AI505286, anticorps growth factor receptor bound protein 14, anticorps GRB14, anticorps grb14, anticorps Grb14
    Sujet

    Background: Adapter protein which modulates coupling of cell surface receptor kinases with specific signaling pathways. Binds to, and suppresses signals from, the activated insulin receptor (INSR). Potent inhibitor of insulin-stimulated MAPK3 phosphorylation. Plays a critical role regulating PDPK1 membrane translocation in response to insulin stimulation and serves as an adapter protein to recruit PDPK1 to activated insulin receptor, thus promoting PKB/AKT1 phosphorylation and transduction of the insulin signal.

    Aliases: GRB14Growth factor receptor-bound protein 14 antibody, GRB14 adapter protein antibody

    UniProt
    Q14449
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