GRB14 anticorps (AA 294-397)
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- Antigène Voir toutes GRB14 Anticorps
- GRB14 (Growth Factor Receptor-Bound Protein 14 (GRB14))
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Épitope
- AA 294-397
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp GRB14 est non-conjugé
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Application
- ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- Réactivité croisée
- Humain
- Purification
- >95%, Protein G purified
- Immunogène
- Recombinant Human Growth factor receptor-bound protein 14 protein (294-397AA)
- Isotype
- IgG
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- Indications d'application
- Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Antigène
- GRB14 (Growth Factor Receptor-Bound Protein 14 (GRB14))
- Autre désignation
- GRB14 (GRB14 Produits)
- Synonymes
- anticorps GRB14, anticorps AI505286, anticorps growth factor receptor bound protein 14, anticorps GRB14, anticorps grb14, anticorps Grb14
- Sujet
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Background: Adapter protein which modulates coupling of cell surface receptor kinases with specific signaling pathways. Binds to, and suppresses signals from, the activated insulin receptor (INSR). Potent inhibitor of insulin-stimulated MAPK3 phosphorylation. Plays a critical role regulating PDPK1 membrane translocation in response to insulin stimulation and serves as an adapter protein to recruit PDPK1 to activated insulin receptor, thus promoting PKB/AKT1 phosphorylation and transduction of the insulin signal.
Aliases: GRB14Growth factor receptor-bound protein 14 antibody, GRB14 adapter protein antibody
- UniProt
- Q14449
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