GRB7 anticorps (AA 233-532)

N° du produit ABIN7154506

Détail du produit anti-GRB7 anticorps

Antigène: GRB7 (Growth Factor Receptor-Bound Protein 7 (GRB7))

Épitope: AA 233-532

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GRB7 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Réactivité croisée: Humain, Rat

Purification: Antigen Affinity Purified

Immunogène: Recombinant Human Growth factor receptor-bound protein 7 protein (233-532AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:200-1:1000, IHC:1:20-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur GRB7

Antigène: GRB7 (Growth Factor Receptor-Bound Protein 7 (GRB7))

Autre désignation: GRB7 (GRB7 Produits)

Synonymes: anticorps GRB7, anticorps mKIAA4028, anticorps growth factor receptor bound protein 7, anticorps GRB7, anticorps Grb7

Sujet:

Background: Adapter protein that interacts with the cytoplasmic domain of numerous receptor kinases and modulates down-stream signaling. Promotes activation of down-stream protein kinases, including STAT3, AKT1, MAPK1 and/or MAPK3. Promotes activation of HRAS. Plays a role in signal transduction in response to EGF. Plays a role in the regulation of cell proliferation and cell migration. Plays a role in the assembly and stability of RNA stress granules. Binds to the 5\\\'UTR of target mRNA molecules and represses translation of target mRNA species, when not phosphorylated. Phosphorylation impairs RNA binding and promotes stress granule disassembly during recovery after cellular stress (By similarity).

Aliases: B47 antibody, Epidermal growth factor receptor GRB 7 antibody, Epidermal growth factor receptor GRB-7 antibody, GRB7 adapter protein antibody, GRB7 antibody, GRB7_HUMAN antibody, Growth factor receptor bound protein 7 antibody, Growth factor receptor-bound protein 7 antibody, OTTHUMP00000164349 antibody, OTTHUMP00000164350 antibody, OTTHUMP00000164351 antibody, OTTHUMP00000164352 antibody

UniProt: Q14451

Pathways: EGFR Signaling Pathway, Ribonucleoprotein Complex Subunit Organization