GNAS anticorps (AA 1-394)

N° du produit ABIN7154707

Détail du produit anti-GNAS anticorps

Antigène: GNAS (GNAS Complex Locus (GNAS))

Épitope: AA 1-394

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GNAS est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Réactivité croisée: Humain, Souris, Rat

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Guanine nucleotide-binding protein G(s) subunit alpha isoforms short protein (1-394AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur GNAS

Antigène: GNAS (GNAS Complex Locus (GNAS))

Autre désignation: GNAS (GNAS Produits)

Synonymes: anticorps AHO, anticorps C20orf45, anticorps GNAS1, anticorps GPSA, anticorps GSA, anticorps GSP, anticorps NESP, anticorps PHP1A, anticorps PHP1B, anticorps PHP1C, anticorps POH, anticorps GNAS, anticorps PORGSA1, anticorps G-alpha-S, anticorps 5530400H20Rik, anticorps A930027G11Rik, anticorps C130027O20Rik, anticorps Galphas, anticorps Gnas1, anticorps Gnasxl, anticorps Gsa, anticorps Nesp, anticorps Nespl, anticorps Oed-Sml, anticorps Oedsml, anticorps P1, anticorps P2, anticorps P3, anticorps G-alpha-s, anticorps gnas-a, anticorps Gnpas, anticorps Nesp55, anticorps gnal, anticorps Gnas, anticorps GNAS complex locus, anticorps guanine nucleotide-binding protein G(s) subunit alpha, anticorps GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus, anticorps GNAS complex locus S homeolog, anticorps neuroendocrine secretory protein 55-like, anticorps GNAS, anticorps LOC694289, anticorps LOC469986, anticorps Gnas, anticorps gnas.S, anticorps gnas, anticorps LOC100346323, anticorps LOC100442753, anticorps LOC100732436

Sujet:

Background: Guanine nucleotide-binding proteins (G proteins) function as transducers in numerous signaling pathways controlled by G protein-coupled receptors (GPCRs) (PubMed:17110384). Signaling involves the activation of adenylyl cyclases, resulting in increased levels of the signaling molecule cAMP (PubMed:26206488, PubMed:8702665). GNAS functions downstream of several GPCRs, including beta-adrenergic receptors (PubMed:21488135). Stimulates the Ras signaling pathway via RAPGEF2 (PubMed:12391161).

Aliases: Adenylate cyclase-stimulating G alpha protein antibody, AHO antibody, alternative gene product encoded by XL-exon antibody, C20orf45 antibody, extra large alphas protein antibody, GNAS antibody, GNAS complex locus antibody, GNAS1 antibody, GNAS1 gene, formerly antibody, GNAS1, formerly antibody, GNAS2_HUMAN antibody, GPSA antibody, GSA antibody, GSP antibody, guanine nucleotide binding protein (G protein), alpha stimulating activity polypeptide 1 antibody, guanine nucleotide regulatory protein antibody, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short antibody, guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas antibody, NESP antibody, neuroendocrine secretory protein antibody, PHP1A antibody, PHP1B antibody, PHP1C antibody, POH antibody, protein ALEX antibody, secretogranin VI antibody

UniProt: P63092

Pathways: Thyroid Hormone Synthesis, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Embryonic Body Morphogenesis