GNL3L anticorps (AA 1-582) (Biotin)

N° du produit ABIN7154758

Détail du produit anti-GNL3L anticorps (Biotin)

Antigène: GNL3L (Guanine Nucleotide Binding Protein-Like 3 (Nucleolar)-Like (GNL3L))

Épitope: AA 1-582

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GNL3L est conjugé à/à la Biotin

Application: ELISA

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Guanine nucleotide-binding protein-like 3-like protein (1-582AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur GNL3L

Antigène: GNL3L (Guanine Nucleotide Binding Protein-Like 3 (Nucleolar)-Like (GNL3L))

Autre désignation: GNL3L (GNL3L Produits)

Synonymes: anticorps SI:zK13A21.8, anticorps flj10613, anticorps flj10613l, anticorps si:dkey-13a21.8, anticorps zgc:110536, anticorps BC020354, anticorps guanine nucleotide binding protein-like 3 (nucleolar)-like, anticorps guanine nucleotide binding protein-like 3 (nucleolar)-like S homeolog, anticorps G protein nucleolar 3 like, anticorps gnl3l, anticorps gnl3l.S, anticorps GNL3L, anticorps Gnl3l

Sujet:

Background: Stabilizes TERF1 telomeric association by preventing TERF1 recruitment by PML. Stabilizes TERF1 protein by preventing its ubiquitination and hence proteasomal degradation. Does so by interfering with TERF1-binding to FBXO4 E3 ubiquitin-protein ligase. Required for cell proliferation. By stabilizing TRF1 protein during mitosis, promotes metaphase-to-anaphase transition. Stabilizes MDM2 protein by preventing its ubiquitination, and hence proteasomal degradation. By acting on MDM2, may affect TP53 activity. Required for normal processing of ribosomal pre-rRNA. Binds GTP.

Aliases: GNL3LGuanine nucleotide-binding protein-like 3-like protein antibody

UniProt: Q9NVN8