HEY1 anticorps (AA 200-300) (Biotin)

N° du produit ABIN7154815

Détail du produit anti-HEY1 anticorps (Biotin)

Antigène: HEY1 (Ha-Ry/enhancer-of-Split Related with YRPW Motif 1 (HEY1))

Épitope: AA 200-300

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HEY1 est conjugé à/à la Biotin

Application: ELISA

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Hairy/enhancer-of-split related with YRPW motif protein 1 protein (200-300AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur HEY1

Antigène: HEY1 (Ha-Ry/enhancer-of-Split Related with YRPW Motif 1 (HEY1))

Autre désignation: HEY1 (HEY1 Produits)

Synonymes: anticorps BHLHb31, anticorps CHF2, anticorps HERP2, anticorps HESR1, anticorps HRT-1, anticorps OAF1, anticorps AI316788, anticorps AI414254, anticorps HRT1, anticorps Herp2, anticorps Hesr1, anticorps bHLHb31, anticorps hesr-1, anticorps id:ibd1292, anticorps zgc:110572, anticorps bc8, anticorps chf2, anticorps herp2, anticorps hesr1, anticorps hrt1, anticorps oaf1, anticorps xbc8, anticorps hes related family bHLH transcription factor with YRPW motif 1, anticorps hairy/enhancer-of-split related with YRPW motif 1, anticorps hes-related family bHLH transcription factor with YRPW motif 1, anticorps hes related family bHLH transcription factor with YRPW motif 1 S homeolog, anticorps HEY1, anticorps Hey1, anticorps hey1, anticorps hey1.S

Sujet:

Background: Transcriptional repressor which binds preferentially to the canonical E box sequence 5\'-CACGTG-3\' (PubMed:11095750). Downstream effector of Notch signaling required for cardiovascular development. Specifically required for the Notch-induced endocardial epithelial to mesenchymal transition, which is itself criticial for cardiac valve and septum development. May be required in conjunction with HEY2 to specify arterial cell fate or identity. Promotes maintenance of neuronal precursor cells and glial versus neuronal fate specification. Represses transcription by the cardiac transcriptional activators GATA4 and GATA6 and by the neuronal bHLH factors ASCL1/MASH1 and NEUROD4/MATH3 (PubMed:15485867). Involved in the regulation of liver cancer cells self-renewal (PubMed:25985737).

Aliases: Basic helix loop helix protein OAF1 antibody, bHLHb31 antibody, Cardiovascular helix loop-helix factor 2 antibody, Cardiovascular helix-loop-helix factor 2 antibody, CHF-2 antibody, CHF2 antibody, Class B basic helix-loop-helix protein 31 antibody, Hairy and enhancer of split related protein 1 antibody, Hairy and enhancer of split-related protein 1 antibody, Hairy enhancer-of-split related with YRPW motif protein 1 antibody, Hairy related transcription factor 1 antibody, Hairy-related transcription factor 1 antibody, Hairy/enhancer of split related with YRPW motif 1 antibody, Hairy/enhancer-of-split related with YRPW motif protein 1 antibody, HERP2 antibody, HES related repressor protein 1 antibody, HES-related repressor protein 1 antibody, HES-related repressor protein 2 antibody, HESR-1 antibody, HESR1 antibody, HEY 1 antibody, hey1 antibody, HEY1_HUMAN antibody, hHRT1 antibody, HRT-1 antibody, HRT1 antibody, OAF1 antibody

UniProt: Q9Y5J3

Pathways: Tube Formation