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Hsc70 anticorps (AA 2-646)

HSPA8 Reactivité: Humain WB, IHC, ELISA, IF, FACS Hôte: Souris Monoclonal 6E4D2 unconjugated
N° du produit ABIN7154884
  • Antigène Voir toutes Hsc70 (HSPA8) Anticorps
    Hsc70 (HSPA8) (Heat Shock 70kDa Protein 8 (HSPA8))
    Épitope
    • 14
    • 7
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 2-646
    Reactivité
    • 82
    • 47
    • 43
    • 21
    • 17
    • 14
    • 13
    • 11
    • 11
    • 11
    • 10
    • 10
    • 5
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 71
    • 27
    • 7
    • 2
    Souris
    Clonalité
    • 68
    • 38
    Monoclonal
    Conjugué
    • 59
    • 19
    • 11
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Hsc70 est non-conjugé
    Application
    • 93
    • 50
    • 39
    • 30
    • 29
    • 28
    • 16
    • 13
    • 11
    • 11
    • 11
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)
     Réactivité croisée
    Humain
    Purification
    Protein G purified
    Immunogène
    Recombinant Human Heat shock cognate 71 kDa protein (2-646AA)
    Clone
    6E4D2
    Isotype
    IgG1, IgG1 kappa
  • Indications d'application
    Recommended dilution: WB: 1:5000-1:32000, IHC: 1:100-1:500, IF: 1:100-1:300, FC: 1:100-1:300,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Antigène
    Hsc70 (HSPA8) (Heat Shock 70kDa Protein 8 (HSPA8))
    Autre désignation
    HSPA8 (HSPA8 Produits)
    Sujet

    Background: Acts as a repressor of transcriptional activation. Inhibits the transcriptional coactivator activity of CITED1 on Smad-mediated transcription. Chaperone. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. May have a scaffolding role in the spliceosome assembly as it contacts all other components of the core complex. Binds bacterial lipopolysaccharide (LPS) et mediates LPS-induced inflammatory response, including TNF secretion by monocytes. Participates in the ER-associated degradation (ERAD) quality control pathway in conjunction with J domain-containing co-chaperones and the E3 ligase CHIP

    Aliases: Heat shock cognate 71 kDa protein (Heat shock 70 kDa protein 8) (Lipopolysaccharide-associated protein 1) (LAP-1) (LPS-associated protein 1), HSPA8, HSC70 HSP73 HSPA10

    UniProt
    P11142
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