HNRNPD/AUF1 anticorps (AA 18-355)

N° du produit ABIN7155104

Détail du produit anti-HNRNPD/AUF1 anticorps

Antigène: HNRNPD/AUF1 (HNRNPD) (Heterogeneous Nuclear Ribonucleoprotein D (HNRNPD))

Épitope: AA 18-355

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HNRNPD/AUF1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Heterogeneous nuclear ribonucleoprotein D0 protein (18-355AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur HNRNPD/AUF1

Antigène: HNRNPD/AUF1 (HNRNPD) (Heterogeneous Nuclear Ribonucleoprotein D (HNRNPD))

Autre désignation: HNRNPD (HNRNPD Produits)

Sujet:

Background: Binds with high affinity to RNA molecules that contain AU-rich elements (AREs) found within the 3\\\'-UTR of many proto-oncogenes and cytokine mRNAs. Also binds to double- and single-stranded DNA sequences in a specific manner and functions a transcription factor. Each of the RNA-binding domains specifically can bind solely to a single-stranded non-monotonous 5\\\'-UUAG-3\\\' sequence and also weaker to the single-stranded 5\\\'-TTAGGG-3\\\' telomeric DNA repeat. Binds RNA oligonucleotides with 5\\\'-UUAGGG-3\\\' repeats more tightly than the telomeric single-stranded DNA 5\\\'-TTAGGG-3\\\' repeats. Binding of RRM1 to DNA inhibits the formation of DNA quadruplex structure which may play a role in telomere elongation. May be involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain.

Aliases: ARE binding protein AUFI type A antibody, AU-rich element RNA-binding protein 1 antibody, AUF antibody, AUF1 antibody, AUF1A antibody, Heterogeneous nuclear ribonucleoprotein D0 antibody, hnRNP D antibody, hnRNP D0 antibody, Hnrnpd antibody, hnRNPD0 antibody, HNRPD antibody, HNRPD_HUMAN antibody, P37 antibody

UniProt: Q14103