HDAC3 anticorps (AA 1-428)
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- Antigène Voir toutes HDAC3 Anticorps
- HDAC3 (Histone Deacetylase 3 (HDAC3))
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Épitope
- AA 1-428
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp HDAC3 est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Chromatin Immunoprecipitation (ChIP)
- Réactivité croisée
- Humain, Souris
- Purification
- >95%, Protein G purified
- Immunogène
- Recombinant Human Histone deacetylase 3 protein (1-428AA)
- Isotype
- IgG
- Top Product
- Discover our top product HDAC3 Anticorps primaire
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- Indications d'application
- Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200, IF:1:50-1:200,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Antigène
- HDAC3 (Histone Deacetylase 3 (HDAC3))
- Autre désignation
- HDAC3 (HDAC3 Produits)
- Sujet
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Background: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Participates in the BCL6 transcriptional repressor activity by deacetylating the H3 \\\'Lys-27\\\' (H3K27) on enhancer elements, antagonizing EP300 acetyltransferase activity and repressing proximal gene expression. Probably participates in the regulation of transcription through its binding to the zinc-finger transcription factor YY1, increases YY1 repression activity. Required to repress transcription of the POU1F1 transcription factor. Acts as a molecular chaperone for shuttling phosphorylated NR2C1 to PML bodies for sumoylation.
Aliases: HD3 antibody, HDAC 3 antibody, HDAC3 antibody, HDAC3_HUMAN antibody, Histone deacetylase 3 antibody, RPD3 2 antibody, RPD3 antibody, RPD3-2 antibody, SMAP45 antibody
- UniProt
- O15379
- Pathways
- Neurotrophin Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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