H2AFB1 anticorps (AA 1-115) (Biotin)

N° du produit ABIN7155374

Détail du produit anti-H2AFB1 anticorps (Biotin)

Antigène: H2AFB1 (H2A Histone Family, Member B1 (H2AFB1))

Épitope: AA 1-115

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp H2AFB1 est conjugé à/à la Biotin

Application: ELISA

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Histone H2A-Bbd type 1 protein (1-115AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur H2AFB1

Antigène: H2AFB1 (H2A Histone Family, Member B1 (H2AFB1))

Autre désignation: H2AFB1 (H2AFB1 Produits)

Synonymes: anticorps H2A.Bbd, anticorps H2A histone family member B1, anticorps H2AFB1

Sujet:

Background: Atypical histone H2A which can replace conventional H2A in some nucleosomes and is associated with active transcription and mRNA processing. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. Nucleosomes containing this histone are less rigid and organize less DNA than canonical nucleosomes in vivo. They are enriched in actively transcribed genes and associate with the elongating form of RNA polymerase. They associate with spliceosome components and are required for mRNA splicing. May participate in spermatogenesis.

Aliases: H2AB1 antibody, H2AFB1 antibody, Histone H2A-Bbd type 1 antibody, H2A Barr body-deficient antibody, H2A.B antibody, H2A.Bbd antibody

UniProt: P0C5Y9

Pathways: Telomere Maintenance