Lysine (K)-Specific Methyltransferase 2B (KMT2B) (AA 145-290) anticorps

N° du produit ABIN7155462

Détail du produit

Antigène: Lysine (K)-Specific Methyltransferase 2B (KMT2B)

Épitope: AA 145-290

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: ELISA, Immunofluorescence (IF)

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Histone-lysine N-methyltransferase 2B protein (145-290AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IF:1:50-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détail du antigène

Antigène: Lysine (K)-Specific Methyltransferase 2B (KMT2B)

Autre désignation: KMT2B (KMT2B Produits)

Synonymes: anticorps HRX2, anticorps MLL1B, anticorps MLL2, anticorps MLL4, anticorps TRX2, anticorps WBP7, anticorps lysine methyltransferase 2B, anticorps KMT2B

Sujet:

Background: Histone methyltransferase. Methylates \'Lys-4\' of histone H3. H3 \'Lys-4\' methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in beta-globin locus transcription regulation by being recruited by NFE2. Plays an important role in controlling bulk H3K4me during oocyte growth and preimplantation development. Required during the transcriptionally active period of oocyte growth for the establishment and/or maintenance of bulk H3K4 trimethylation (H3K4me3), global transcriptional silencing that preceeds resumption of meiosis, oocyte survival and normal zygotic genome activation.

Aliases: Histone-lysine N-methyltransferase 2B antibody, HRX2 antibody, KIAA0304 gene product antibody, KMT2B antibody, KMT2B_HUMAN antibody, Likely ortholog of mouse WW domain binding protein 7 antibody, Lysine N-methyltransferase 2B antibody, mixed lineage leukemia 4 antibody, Mixed lineage leukemia gene homolog 2 protein antibody, MLL2 antibody, myeloid lymphoid leukemia 4 antibody, Myeloid lymphoid or mixed lineage leukemia protein 4 antibody, Myeloid/lymphoid or mixed-lineage leukemia protein 4 antibody, Trithorax homolog 2 antibody, trithorax homologue 2 antibody, TRX2 antibody, WBP-7 antibody, WBP7 antibody, WW domain-binding protein 7 antibody

UniProt: Q9UMN6

Pathways: L'effet Warburg