EZH1 anticorps (AA 160-280)
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- Antigène Voir toutes EZH1 Anticorps
- EZH1 (Enhancer of Zeste Homolog 1 (EZH1))
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Épitope
- AA 160-280
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp EZH1 est non-conjugé
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Application
- ELISA, Immunohistochemistry (IHC)
- Réactivité croisée
- Humain
- Purification
- Antigen Affinity Purified
- Immunogène
- Recombinant Human Histone-lysine N-methyltransferase EZH1 protein (160-280AA)
- Isotype
- IgG
- Top Product
- Discover our top product EZH1 Anticorps primaire
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- Indications d'application
- Recommended dilution: IHC:1:20-1:200,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Antigène
- EZH1 (Enhancer of Zeste Homolog 1 (EZH1))
- Autre désignation
- EZH1 (EZH1 Produits)
- Synonymes
- anticorps KMT6B, anticorps si:ch211-250i3.1, anticorps zgc:136829, anticorps AW557915, anticorps mKIAA0388, anticorps EZH1, anticorps enhancer of zeste 1 polycomb repressive complex 2 subunit, anticorps EZH1, anticorps ezh1, anticorps Ezh1
- Sujet
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Background: Polycomb group (PcG) protein. Catalytic subunit of the PRC2/EED-EZH1 complex, which methylates \\\'Lys-27\\\' of histone H3, leading to transcriptional repression of the affected target gene. Able to mono-, di- and trimethylate \\\'Lys-27\\\' of histone H3 to form H3K27me1, H3K27me2 and H3K27me3, respectively. Required for embryonic stem cell derivation and self-renewal, suggesting that it is involved in safeguarding embryonic stem cell identity. Compared to EZH2-containing complexes, it is less abundant in embryonic stem cells, has weak methyltransferase activity and plays a less critical role in forming H3K27me3, which is required for embryonic stem cell identity and proper differentiation.
Aliases: Enhancer of zeste homolog 1 (Drosophila) antibody, Enhancer of zeste homolog 1 antibody, ENX-2 antibody, ENX2 antibody, Ezh1 antibody, EZH1_HUMAN antibody, Histone-lysine N-methyltransferase EZH1 antibody
- UniProt
- Q92800
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