HIPK1 anticorps (AA 1007-1151)

N° du produit ABIN7155861

Détail du produit anti-HIPK1 anticorps

Antigène: HIPK1 (Homeodomain Interacting Protein Kinase 1 (HIPK1))

Épitope: AA 1007-1151

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HIPK1 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Homeodomain-interacting protein kinase 1 protein (1007-1151AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:200-1:500, IF:1:50-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur HIPK1

Antigène: HIPK1 (Homeodomain Interacting Protein Kinase 1 (HIPK1))

Autre désignation: HIPK1 (HIPK1 Produits)

Synonymes: anticorps HIPK1, anticorps myak, anticorps nbak2, anticorps hipk1, anticorps Myak, anticorps Nbak2, anticorps 1110062K04Rik, anticorps homeodomain interacting protein kinase 1, anticorps homeodomain interacting protein kinase 1 L homeolog, anticorps homeodomain interacting protein kinase 1 S homeolog, anticorps HIPK1, anticorps hipk1.L, anticorps hipk1, anticorps hipk1.S, anticorps Hipk1

Sujet:

Background: Serine/threonine-protein kinase involved in transcription regulation and TNF-mediated cellular apoptosis. Plays a role as a corepressor for homeodomain transcription factors. Phosphorylates DAXX and MYB. Phosphorylates DAXX in response to stress, and mediates its translocation from the nucleus to the cytoplasm. Inactivates MYB transcription factor activity by phosphorylation. Prevents MAP3K5-JNK activation in the absence of TNF. TNF triggers its translocation to the cytoplasm in response to stress stimuli, thus activating nuclear MAP3K5-JNK by derepression and promoting apoptosis. May be involved in anti-oxidative stress responses. Involved in the regulation of eye size, lens formation and retinal lamination during late embryogenesis. Promotes angiogenesis and to be involved in erythroid differentiation. May be involved in malignant squamous cell tumor formation.

Aliases: Hipk 1 antibody, Hipk1 antibody, HIPK1_HUMAN antibody, Homeodomain interacting protein kinase 1 antibody, Homeodomain interacting protein kinase 1 like protein antibody, Homeodomain-interacting protein kinase 1 antibody, Myak antibody, Nbak 2 antibody, Nbak2 antibody, Nuclear body associated kinase 2 antibody, Nuclear body associated kinase 2b antibody

UniProt: Q86Z02