HIPK3 anticorps (AA 841-1130)

N° du produit ABIN7155869

Détail du produit anti-HIPK3 anticorps

Antigène: HIPK3 (Homeodomain Interacting Protein Kinase 3 (HIPK3))

Épitope: AA 841-1130

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HIPK3 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Homeodomain-interacting protein kinase 3 protein (841-1130AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur HIPK3

Antigène: HIPK3 (Homeodomain Interacting Protein Kinase 3 (HIPK3))

Autre désignation: HIPK3 (HIPK3 Produits)

Synonymes: anticorps HIPK3, anticorps pky, anticorps yak1, anticorps dyrk6, anticorps fist3, anticorps MGC145460, anticorps DYRK6, anticorps FIST3, anticorps PKY, anticorps YAK1, anticorps ANPK, anticorps homeodomain interacting protein kinase 3, anticorps homeodomain interacting protein kinase 3 L homeolog, anticorps HIPK3, anticorps hipk3.L, anticorps hipk3, anticorps Hipk3

Sujet:

Background: Serine/threonine-protein kinase involved in transcription regulation, apoptosis and steroidogenic gene expression. Phosphorylates JUN and RUNX2. Seems to negatively regulate apoptosis by promoting FADD phosphorylation. Enhances androgen receptor-mediated transcription. May act as a transcriptional corepressor for NK homeodomain transcription factors. The phosphorylation of NR5A1 activates SF1 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. In osteoblasts, supports transcription activation: phosphorylates RUNX2 that synergizes with SPEN/MINT to enhance FGFR2-mediated activation of the osteocalcin FGF-responsive element (OCFRE).

Aliases: Androgen receptor interacting nuclear protein kinase antibody, Androgen receptor-interacting nuclear protein kinase antibody, ANPK antibody, DYRK6 antibody, Fas interacting serine/threonine protein kinase antibody, Fas-interacting serine/threonine-protein kinase antibody, FIST antibody, FIST3 antibody, Hipk3 antibody, HIPK3_HUMAN antibody, homeodomain interacting protein kinase 3 antibody, Homeodomain-interacting protein kinase 3 antibody, Homolog of protein kinase YAK1 antibody, PKY antibody, RP24 297H17.5 antibody, YAK1 antibody

UniProt: Q9H422