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HIPK3 anticorps (AA 841-1130) (Biotin)

HIPK3 Reactivité: Humain ELISA Hôte: Lapin Polyclonal Biotin
N° du produit ABIN7155870
  • Antigène Voir toutes HIPK3 Anticorps
    HIPK3 (Homeodomain Interacting Protein Kinase 3 (HIPK3))
    Épitope
    • 15
    • 8
    • 5
    • 4
    • 4
    • 1
    • 1
    • 1
    AA 841-1130
    Reactivité
    • 38
    • 2
    • 2
    Humain
    Hôte
    • 38
    Lapin
    Clonalité
    • 38
    Polyclonal
    Conjugué
    • 12
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp HIPK3 est conjugé à/à la Biotin
    Application
    • 20
    • 15
    • 13
    • 13
    • 13
    • 7
    • 3
    • 2
    • 1
    • 1
    ELISA
     Réactivité croisée
    Humain
    Purification
    >95%, Protein G purified
    Immunogène
    Recombinant Human Homeodomain-interacting protein kinase 3 protein (841-1130AA)
    Isotype
    IgG
    Top Product
    Discover our top product HIPK3 Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Antigène
    HIPK3 (Homeodomain Interacting Protein Kinase 3 (HIPK3))
    Autre désignation
    HIPK3 (HIPK3 Produits)
    Sujet

    Background: Serine/threonine-protein kinase involved in transcription regulation, apoptosis and steroidogenic gene expression. Phosphorylates JUN and RUNX2. Seems to negatively regulate apoptosis by promoting FADD phosphorylation. Enhances androgen receptor-mediated transcription. May act as a transcriptional corepressor for NK homeodomain transcription factors. The phosphorylation of NR5A1 activates SF1 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. In osteoblasts, supports transcription activation: phosphorylates RUNX2 that synergizes with SPEN/MINT to enhance FGFR2-mediated activation of the osteocalcin FGF-responsive element (OCFRE).

    Aliases: Androgen receptor interacting nuclear protein kinase antibody, Androgen receptor-interacting nuclear protein kinase antibody, ANPK antibody, DYRK6 antibody, Fas interacting serine/threonine protein kinase antibody, Fas-interacting serine/threonine-protein kinase antibody, FIST antibody, FIST3 antibody, Hipk3 antibody, HIPK3_HUMAN antibody, homeodomain interacting protein kinase 3 antibody, Homeodomain-interacting protein kinase 3 antibody, Homolog of protein kinase YAK1 antibody, PKY antibody, RP24 297H17.5 antibody, YAK1 antibody

    UniProt
    Q9H422
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