HOMER1 anticorps (AA 1-354) (HRP)

N° du produit ABIN7155880

Détail du produit anti-HOMER1 anticorps (HRP)

Antigène: HOMER1 (Homer Homolog 1 (HOMER1))

Épitope: AA 1-354

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HOMER1 est conjugé à/à la HRP

Application: ELISA

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Homer protein homolog 1 protein (1-354AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur HOMER1

Antigène: HOMER1 (Homer Homolog 1 (HOMER1))

Autre désignation: HOMER1 (HOMER1 Produits)

Synonymes: anticorps HOMER, anticorps HOMER1A, anticorps HOMER1B, anticorps HOMER1C, anticorps SYN47, anticorps Ves-1, anticorps HOMER1, anticorps PSD-Zip45, anticorps homer1, anticorps zgc:100854, anticorps zgc:92844, anticorps HOMER1F, anticorps Vesl-1, anticorps homer, anticorps xhomer1, anticorps BEST:LD03829, anticorps CG11324, anticorps Dhom, anticorps Dhomer, anticorps Dm Homer, anticorps Dmel\CG11324, anticorps Dvh, anticorps Hom, anticorps Homer, anticorps LD03829, anticorps dhom, anticorps homer scaffolding protein 1, anticorps homer scaffolding protein 1b, anticorps homer scaffolding protein 1 L homeolog, anticorps CG11324 gene product from transcript CG11324-RD, anticorps HOMER1, anticorps Homer1, anticorps homer1b, anticorps homer1.L, anticorps homer

Sujet:

Background: Postsynaptic density scaffolding protein. Binds and cross-links cytoplasmic regions of GRM1, GRM5, ITPR1, DNM3, RYR1, RYR2, SHANK1 and SHANK3. By physically linking GRM1 and GRM5 with ER-associated ITPR1 receptors, it aids the coupling of surface receptors to intracellular calcium release. May also couple GRM1 to PI3 kinase through its interaction with AGAP2. Isoform 1 regulates the trafficking and surface expression of GRM5. Isoform 3 acts as a natural dominant negative, in dynamic competition with constitutively expressed isoform 1 to regulate synaptic metabotropic glutamate function. Isoform 3, may be involved in the structural changes that occur at synapses during long-lasting neuronal plasticity and development. Forms a high-order complex with SHANK1, which in turn is necessary for the structural and functional integrity of dendritic spines (By similarity).

Aliases: HOME1_HUMAN antibody, Homer antibody, HOMER 1A antibody, HOMER 1B antibody, HOMER 1C antibody, Homer homolog 1 (Drosophila) antibody, homer homolog 1 antibody, Homer protein homolog 1 antibody, homer scaffolding protein 1 antibody, Homer, Drosophila, homolog of, 1 antibody, Homer, neuronal immediate early gene, 1 antibody, Homer-1 antibody, Homer1 antibody, HOMER1A antibody, HOMER1B antibody, HOMER1C antibody, SYN47 antibody, Ves 1 antibody

UniProt: Q86YM7

Pathways: Skeletal Muscle Fiber Development