IgD anticorps (AA 1-240)
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- Antigène Voir toutes IgD Anticorps
- IgD
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Épitope
- AA 1-240
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp IgD est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Réactivité croisée
- Humain, Souris
- Purification
- >95%, Protein G purified
- Immunogène
- Recombinant Human Ig delta chain C region protein (1-240AA)
- Isotype
- IgG
- Top Product
- Discover our top product IgD Anticorps primaire
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- Indications d'application
- Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Antigène
- IgD
- Autre désignation
- IGHD (IgD Produits)
- Synonymes
- anticorps IgD, anticorps Igh-5, anticorps immunoglobulin heavy constant delta, anticorps immunoglobulin delta heavy chain constant region, anticorps Ighd, anticorps Igd, anticorps IGHD
- Classe de substances
- Antibody
- Sujet
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Background: IgD is the major antigen receptor isotype on the surface of most peripheral B-cells, where it is coexpressed with IgM. The membrane-bound IgD (mIgD) induces the phosphorylation of CD79A and CD79B by the Src family of protein tyrosine kinases. Soluble IgD (sIgD) concentration in serum below those of IgG, IgA, and IgM but much higher than that of IgE. IgM and IgD molecules present on B cells have identical V regions and antigen-binding sites. After the antigen binds to the B-cell receptor, the secreted form sIgD is shut off. IgD is a potent inducer of TNF, IL1B, and IL1RN. IgD also induces release of IL6, IL10, and LIF from peripheral blood mononuclear cells. Monocytes seem to be the main producers of cytokines in vitro in the presence of IgD.
Aliases: IGHD antibody, Immunoglobulin heavy constant delta antibody, Ig delta chain C region antibody, Ig delta chain C region NIG-65 antibody, Ig delta chain C region WAH antibody
- UniProt
- P01880
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