KPNA2 anticorps (AA 2-285)
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- Antigène Voir toutes KPNA2 Anticorps
- KPNA2 (Karyopherin alpha 2 (RAG Cohort 1, Importin alpha 1) (KPNA2))
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Épitope
- AA 2-285
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp KPNA2 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
- Réactivité croisée
- Humain
- Purification
- >95%, Protein G purified
- Immunogène
- Recombinant Human Importin subunit alpha-1 protein (2-285AA)
- Isotype
- IgG
- Top Product
- Discover our top product KPNA2 Anticorps primaire
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- Indications d'application
- Recommended dilution: WB:1:2000-1:5000, IHC:1:20-1:200, IF:1:50-1:200,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Antigène
- KPNA2 (Karyopherin alpha 2 (RAG Cohort 1, Importin alpha 1) (KPNA2))
- Autre désignation
- KPNA2 (KPNA2 Produits)
- Synonymes
- anticorps IPOA1, anticorps QIP2, anticorps RCH1, anticorps SRP1alpha, anticorps ima2, anticorps importin, anticorps 2410044B12Rik, anticorps PTAC58, anticorps Rch1, anticorps ipoa1, anticorps kpna2, anticorps qip2, anticorps rch1, anticorps srp1alpha, anticorps hm:zeh0389, anticorps hm:zeh0389r, anticorps zgc:113902, anticorps zgc:86945, anticorps karyopherin subunit alpha 2, anticorps importin subunit alpha-2, anticorps Importin subunit alpha-2, anticorps karyopherin (importin) alpha 2, anticorps karyopherin alpha-2 subunit like L homeolog, anticorps karyopherin alpha 2 (RAG cohort 1, importin alpha 1), anticorps KPNA2, anticorps EDI_246290, anticorps EDI_335040, anticorps ima2, anticorps Kpna2, anticorps kpna2.L, anticorps kpna2
- Sujet
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Background: Functions in nuclear protein import as an adapter protein for nuclear receptor KPNB1. Binds specifically and directly to substrates containing either a simple or bipartite NLS motif. Docking of the importin/substrate complex to the nuclear pore complex (NPC) is mediated by KPNB1 through binding to nucleoporin FxFG repeats and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to importin-beta and the three components separate and importin-alpha and -beta are re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran from importin. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus.
Aliases: IMA1_HUMAN antibody, Importin alpha 1 antibody, Importin alpha 2 antibody, Importin alpha 2 subunit antibody, Importin alpha P1 antibody, Importin subunit alpha-1 antibody, IPO A1 antibody, IPOA 1 antibody, IPOA1 antibody, Karyopherin alpha 2 antibody, Karyopherin alpha 2 RAG cohort 1 antibody, Karyopherin alpha 2 subunit antibody, Karyopherin subunit alpha-2 antibody, KPNA2 antibody, KPNA2 protein antibody, Pendulin antibody, QIP 2 antibody, QIP2 antibody, RAG cohort 1 antibody, RAG cohort protein 1 antibody, RCH 1 antibody, RCH1 antibody, SRP 1 antibody, SRP1 alpha antibody, SRP1 antibody, SRP1-alpha antibody, SRP1alpha antibody
- UniProt
- P52292
- Pathways
- M Phase, Protein targeting to Nucleus
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