FKBP6 anticorps (AA 101-327)

N° du produit ABIN7156155

Détail du produit anti-FKBP6 anticorps

Antigène: FKBP6 (FK506 Binding Protein 6, 36kDa (FKBP6))

Épitope: AA 101-327

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FKBP6 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Inactive peptidyl-prolyl cis-trans isomerase FKBP6 protein (101-327AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur FKBP6

Antigène: FKBP6 (FK506 Binding Protein 6, 36kDa (FKBP6))

Autre désignation: FKBP6 (FKBP6 Produits)

Synonymes: anticorps 1700008G22Rik, anticorps 36kDa, anticorps AU017274, anticorps D5Ertd724e, anticorps FKBP-36, anticorps FKBP-6, anticorps PPiase, anticorps FKBP36, anticorps FK506 binding protein 6, anticorps FK506 binding protein 6 L homeolog, anticorps Fkbp6, anticorps fkbp6.L, anticorps FKBP6

Sujet:

Background: Co-chaperone required during spermatogenesis to repress transposable elements and prevent their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Acts as a co-chaperone via its interaction with HSP90 and is required for the piRNA amplification process, the secondary piRNA biogenesis. May be required together with HSP90 in removal of 16 nucleotide ping-pong by-products from Piwi complexes, possibly facilitating turnover of Piwi complexes.

Aliases: 36 kDa FK506 binding protein antibody, 36 kDa FK506-binding protein antibody, 36 kDa FKBP antibody, EC 5.2.1.8 antibody, FK506 binding protein 6 antibody, FK506-binding protein 6 antibody, FKBP 36 antibody, FKBP-36 antibody, FKBP-6 antibody, FKBP36 antibody, fkbp6 antibody, FKBP6_HUMAN antibody, Immunophilin FKBP36 antibody, Peptidyl prolyl cis trans isomerase antibody, Peptidyl-prolyl cis-trans isomerase FKBP6 antibody, PPIase antibody, PPIase FKBP6 antibody, Rotamase antibody

UniProt: O75344

Pathways: M Phase