Plexin B2 anticorps (AA 1458-1673) (Biotin)

N° du produit ABIN7156268

Détail du produit anti-Plexin B2 anticorps (Biotin)

Antigène: Plexin B2 (PLXNB2)

Épitope: AA 1458-1673

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Plexin B2 est conjugé à/à la Biotin

Application: ELISA

Réactivité croisée: Humain

Purification: >95%, Antigen Affinity purified & Affinity purified

Immunogène: Recombinant Human Inhibitor of nuclear factor kappa-B kinase-interacting protein (1458-1673AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur Plexin B2

Antigène: Plexin B2 (PLXNB2)

Autre désignation: PLXNB2 (PLXNB2 Produits)

Synonymes: anticorps PLXNB2, anticorps MM1, anticorps Nbla00445, anticorps PLEXB2, anticorps dJ402G11.3, anticorps 1110007H23Rik, anticorps Debt, anticorps mKIAA0315, anticorps plexin B2, anticorps plexin B2 S homeolog, anticorps PLXNB2, anticorps plxnb2.S, anticorps plxnb2, anticorps Plxnb2

Sujet:

Background: Cell surface receptor for SEMA4C, SEMA4D and SEMA4G that plays an important role in cell-cell signaling. Binding to class 4 semaphorins promotes downstream activation of RHOA and phosphorylation of ERBB2 at \'Tyr-1248\'. Required for normal differentiation and migration of neuronal cells during brain corticogenesis and for normal embryonic brain development. Regulates the migration of cerebellar granule cells in the developing brain. Plays a role in RHOA activation and subsequent changes of the actin cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. May modulate the activity of RAC1 and CDC42. Down-regulates macrophage migration in wound-healing assays (in vitro) (By similarity).

Aliases: PLXNB2 antibody, KIAA0315 antibody, Plexin-B2 antibody, MM1 antibody

UniProt: O15031

Pathways: Tube Formation