IL28RA anticorps (AA 21-228)
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- Antigène Voir toutes IL28RA Anticorps
- IL28RA (Interleukin 28 Receptor, alpha (Interferon, lambda Receptor) (IL28RA))
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Épitope
- AA 21-228
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp IL28RA est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Réactivité croisée
- Humain, Souris
- Purification
- Antigen Affinity Purified
- Immunogène
- Recombinant Human Interferon lambda receptor 1 protein (21-228AA)
- Isotype
- IgG
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- Indications d'application
- Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Antigène
- IL28RA (Interleukin 28 Receptor, alpha (Interferon, lambda Receptor) (IL28RA))
- Autre désignation
- IFNLR1 (IL28RA Produits)
- Synonymes
- anticorps IFNLR1, anticorps IL28RA, anticorps crf2/12, anticorps ifnlr, anticorps il-28r1, anticorps il28ra, anticorps licr2, anticorps ifnlr1, anticorps CRF2-12, anticorps Il28ra, anticorps CRF2/12, anticorps IFNLR, anticorps IL-28R1, anticorps LICR2, anticorps RGD1562689, anticorps interferon lambda receptor 1, anticorps interferon, lambda receptor 1, anticorps interferon, lambda receptor 1 L homeolog, anticorps IFNLR1, anticorps ifnlr1, anticorps ifnlr1.L, anticorps Ifnlr1
- Sujet
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Background: The IFNLR1/IL10RB dimer is a receptor for the cytokine ligands IFNL2 and IFNL3 and mediates their antiviral activity. The ligand/receptor complex stimulate the activation of the JAK/STAT signaling pathway leading to the expression of IFN-stimulated genes (ISG), which contribute to the antiviral state. Determines the cell type specificity of the lambda interferon action. Shows a more restricted pattern of expression in the epithelial tissues thereby limiting responses to lambda interferons primarily to epithelial cells of the respiratory, gastrointestinal, and reproductive tracts. Seems not to be essential for early virus-activated host defense in vaginal infection, but plays an important role in Toll-like receptor (TLR)-induced antiviral defense. Plays a significant role in the antiviral immune defense in the intestinal epithelium.
Aliases: IFNLR1 antibody, IL28RA antibody, LICR2 antibody, Interferon lambda receptor 1 antibody, IFN-lambda receptor 1 antibody, IFN-lambda-R1 antibody, Cytokine receptor class-II member 12 antibody, Cytokine receptor family 2 member 12 antibody, CRF2-12 antibody, Interleukin-28 receptor subunit alpha antibody, IL-28 receptor subunit alpha antibody, IL-28R-alpha antibody, IL-28RA antibody, Likely interleukin or cytokine receptor 2 antibody, LICR2 antibody
- UniProt
- Q8IU57
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