IL29 anticorps (AA 20-200)

N° du produit ABIN7156607

Détail du produit anti-IL29 anticorps

Antigène: IL29 (Interleukin 29 (IL29))

Épitope: AA 20-200

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IL29 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Réactivité croisée: Humain

Purification: Antigen Affinity Purified

Immunogène: Recombinant Human Interferon lambda-1 protein (20-200AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur IL29

Antigène: IL29 (Interleukin 29 (IL29))

Autre désignation: IFNL1 (IL29 Produits)

Synonymes: anticorps IL-29, anticorps IL29, anticorps interferon lambda 1, anticorps interferon lambda-1, anticorps interleukin 29 (interferon, lambda 1), anticorps IFNL1, anticorps LOC612539, anticorps IL29

Sujet:

Background: Cytokine with antiviral, antitumour and immunomodulatory activities. Plays a critical role in the antiviral host defense, predominantly in the epithelial tissues. Acts as a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1, and receptor engagement leads to the activation of the JAK/STAT signaling pathway resulting in the expression of IFN-stimulated genes (ISG), which mediate the antiviral state. Has a restricted receptor distribution and therefore restricted targets: is primarily active in epithelial cells and this cell type-selective action is because of the epithelial cell-specific expression of its receptor IFNLR1. Exerts an immunomodulatory effect by up-regulating MHC class I antigen expression.

Aliases: IFNL1 antibody, IL29 antibody, ZCYTO21Interferon lambda-1 antibody, IFN-lambda-1 antibody, Cytokine Zcyto21 antibody, Interleukin-29 antibody, IL-29 antibody

UniProt: Q8IU54