IRF4 anticorps (AA 180-451)

N° du produit ABIN7156622

Détail du produit anti-IRF4 anticorps

Antigène: IRF4 (Interferon Regulatory Factor 4 (IRF4))

Épitope: AA 180-451

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IRF4 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Réactivité croisée: Humain

Purification: Antigen Affinity Purified

Immunogène: Recombinant Human Interferon regulatory factor 4 protein (180-451AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur IRF4

Antigène: IRF4 (Interferon Regulatory Factor 4 (IRF4))

Autre désignation: IRF4 (IRF4 Produits)

Synonymes: anticorps LSIRF, anticorps MUM1, anticorps NF-EM5, anticorps AI385587, anticorps IRF-4, anticorps Spip, anticorps IRF4, anticorps si:ch73-170d1.2, anticorps irf4, anticorps interferon regulatory factor 4, anticorps interferon regulatory factor 4a, anticorps Interferon regulatory factor 4, anticorps PWWP domain-containing protein MUM1, anticorps IRF4, anticorps Irf4, anticorps irf4a, anticorps irf4, anticorps LOC612320, anticorps LOC100068881

Sujet:

Background: Transcriptional activator. Binds to the interferon-stimulated response element (ISRE) of the MHC class I promoter. Binds the immunoglobulin lambda light chain enhancer, together with PU.1. Probably plays a role in ISRE-targeted signal transduction mechanisms specific to lymphoid cells. Involved in CD8+ dendritic cell differentiation by forming a complex with the BATF-JUNB heterodimer in immune cells, leading to recognition of AICE sequence (5\\\'-TGAnTCA/GAAA-3\\\'), an immune-specific regulatory element, followed by cooperative binding of BATF and IRF4 and activation of genes.

Aliases: Interferon regulatory factor 4 antibody, IRF 4 antibody, IRF-4 antibody, Irf4 antibody, IRF4_HUMAN antibody, LSIRF antibody, Lymphocyte specific interferon regulatory factor antibody, Lymphocyte specific IRF antibody, Lymphocyte-specific interferon regulatory factor antibody, Multiple myeloma oncogene 1 antibody, MUM 1 antibody, MUM1 antibody, NF EM5 antibody, NF-EM5 antibody, NFEM5 antibody, PU.1 interaction partner antibody, Sfpi1/PU.1 interaction partner antibody, Transcriptional activator PIP antibody

UniProt: Q15306

Pathways: Chromatin Binding