IRF8 anticorps (AA 137-426)

N° du produit ABIN7156635

Détail du produit anti-IRF8 anticorps

Antigène: IRF8 (Interferon Regulatory Factor 8 (IRF8))

Épitope: AA 137-426

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IRF8 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Réactivité croisée: Humain

Purification: Antigen Affinity Purified

Immunogène: Recombinant Human Interferon regulatory factor 8 protein (137-426AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur IRF8

Antigène: IRF8 (Interferon Regulatory Factor 8 (IRF8))

Autre désignation: IRF8 (IRF8 Produits)

Synonymes: anticorps zgc:92252, anticorps IRF8, anticorps MGC140338, anticorps DKFZp469B0320, anticorps H-ICSBP, anticorps ICSBP, anticorps ICSBP1, anticorps IRF-8, anticorps icsbp1, anticorps AI893568, anticorps Icsbp1, anticorps Myls, anticorps interferon regulatory factor 8, anticorps interferon regulatory factor 8 L homeolog, anticorps irf8, anticorps IRF8, anticorps irf8.L, anticorps Irf8

Sujet:

Background: Specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS)). Plays a negative regulatory role in cells of the immune system. Involved in CD8+ dendritic cell differentiation by forming a complex with the BATF-JUNB heterodimer in immune cells, leading to recognition of AICE sequence (5\\\'-TGAnTCA/GAAA-3\\\'), an immune-specific regulatory element, followed by cooperative binding of BATF and IRF8 and activation of genes.

Aliases: H ICSBP antibody, H-ICSBP antibody, HGNC:5358 antibody, HICSBP antibody, ICSBP 1 antibody, ICSBP antibody, ICSBP1 antibody, Interferon consensus sequence binding protein 1 antibody, Interferon consensus sequence binding protein antibody, Interferon consensus sequence-binding protein antibody, Interferon regulatory factor 8 antibody, IRF 8 antibody, IRF-8 antibody, Irf8 antibody, IRF8_HUMAN antibody, MYLS antibody

UniProt: Q02556

Pathways: Cellular Response to Molecule of Bacterial Origin