IFIT2 anticorps (AA 130-265)

N° du produit ABIN7156667

Détail du produit anti-IFIT2 anticorps

Antigène: IFIT2 (Interferon-Induced Protein with Tetratricopeptide Repeats 2 (IFIT2))

Épitope: AA 130-265

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IFIT2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Réactivité croisée: Humain, Rat

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Interferon-induced protein with tetratricopeptide repeats 2 protein (130-265AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:500-1:5000, IHC:1:500-1:1000, IF:1:50-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur IFIT2

Antigène: IFIT2 (Interferon-Induced Protein with Tetratricopeptide Repeats 2 (IFIT2))

Autre désignation: IFIT2 (IFIT2 Produits)

Synonymes: anticorps G10P2, anticorps GARG-39, anticorps IFI-54, anticorps IFI-54K, anticorps IFI54, anticorps IFIT-2, anticorps ISG-54 K, anticorps ISG-54K, anticorps ISG54, anticorps P54, anticorps cig42, anticorps wu:fb58d07, anticorps DKFZp468G198, anticorps AV302338, anticorps Ifi54, anticorps interferon induced protein with tetratricopeptide repeats 2, anticorps interferon-induced protein with tetratricopeptide repeats 2, anticorps interferon-induced protein with tetratricopeptide repeats 15, anticorps IFIT2, anticorps Ifit2, anticorps ifit15

Sujet:

Background: IFN-induced antiviral protein which inhibits expression of viral messenger RNAs lacking 2\\\'-O-methylation of the 5\\\' cap. The ribose 2\\\'-O-methylation would provide a molecular signature to distinguish between self and non-self mRNAs by the host during viral infection. Viruses evolved several ways to evade this restriction system such as encoding their own 2\\\'-O-methylase for their mRNAs or by stealing host cap containing the 2\\\'-O-methylation (cap snatching mechanism). Binds AU-rich viral RNAs, with or without 5\\\' triphosphorylation, RNA-binding is required for antiviral activity. Can promote apoptosis.

Aliases: CIG-42 antibody, cig42 antibody, G10P2 antibody, GARG 39 antibody, Glucocorticoid attenuated response gene 39 antibody, IFI 54 antibody, IFI 54K antibody, IFI-54K antibody, IFI54 antibody, IFIT 2 antibody, IFIT-2 antibody, IFIT2 antibody, IFIT2_HUMAN antibody, Interferon induced 54 kDa protein antibody, Interferon induced protein 54 antibody, Interferon induced protein with tetratricopeptide repeats 2 antibody, Interferon, alpha inducible protein (MW 54kD) antibody, Interferon-induced 54 kDa protein antibody, Interferon-induced protein with tetratricopeptide repeats 2 antibody, ISG 54 K antibody, ISG 54K antibody, ISG-54 K antibody, ISG54 antibody

UniProt: P09913