IL23A anticorps (AA 20-155)

N° du produit ABIN7156868

Détail du produit anti-IL23A anticorps

Antigène: IL23A (Interleukin 23, alpha subunit p19 (IL23A))

Épitope: AA 20-155

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IL23A est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Interleukin-23 subunit alpha protein (20-155AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur IL23A

Antigène: IL23A (Interleukin 23, alpha subunit p19 (IL23A))

Autre désignation: IL23A (IL23A Produits)

Synonymes: anticorps IL-23, anticorps IL-23A, anticorps IL23P19, anticorps P19, anticorps SGRF, anticorps FIL1, anticorps FIL1(ZETA), anticorps FIL1Z, anticorps IL-1F7, anticorps IL-1H, anticorps IL-1H4, anticorps IL-1RP1, anticorps IL-37, anticorps IL1F7, anticorps IL1H4, anticorps IL1RP1, anticorps p19, anticorps il23p19, anticorps IL23, anticorps interleukin 23 subunit alpha, anticorps interleukin 37, anticorps interleukin 23, alpha subunit p19, anticorps IL23A, anticorps IL37, anticorps Il23a

Sujet:

Background: Associates with IL12B to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.

Aliases: IL 23 A antibody, IL 23 antibody, IL 23 subunit alpha antibody, IL 23A antibody, IL 23p19 antibody, IL-23 subunit alpha antibody, IL-23-A antibody, IL-23p19 antibody, IL12B antibody, IL23 antibody, Il23a antibody, IL23A_HUMAN antibody, IL23P19 antibody, interleukin 12B antibody, Interleukin 23 alpha subunit p19 antibody, Interleukin 23 p19 subunit antibody, interleukin 23 subunit alpha antibody, interleukin 23 subunit p19 antibody, interleukin six, G CSF related factor antibody, Interleukin-23 subunit alpha antibody, Interleukin-23 subunit p19 antibody, JKA3 induced upon T cell activation antibody, MGC79388 antibody, P19 antibody, SGRF antibody

UniProt: Q9NPF7

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation