ISCU anticorps (AA 1-167)
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- Antigène Voir toutes ISCU Anticorps
- ISCU (Iron-sulfur cluster assembly enzyme ISCU, mitochondrial (ISCU))
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Épitope
- AA 1-167
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp ISCU est non-conjugé
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Application
- ELISA, Immunohistochemistry (IHC)
- Réactivité croisée
- Humain
- Purification
- Antigen Affinity Purified
- Immunogène
- Recombinant Human Iron-sulfur cluster assembly enzyme ISCU, mitochondrial protein (1-167AA)
- Isotype
- IgG
- Top Product
- Discover our top product ISCU Anticorps primaire
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- Indications d'application
- Recommended dilution: IHC:1:20-1:200,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Antigène
- ISCU (Iron-sulfur cluster assembly enzyme ISCU, mitochondrial (ISCU))
- Autre désignation
- ISCU (ISCU Produits)
- Synonymes
- anticorps nifun, anticorps zC191D15.3, anticorps si:ch211-191d15.3, anticorps 2310020H20Rik, anticorps HML, anticorps ISU2, anticorps NIFU, anticorps NIFUN, anticorps hnifU, anticorps RGD1309562, anticorps AA407971, anticorps Nifu, anticorps Nifun, anticorps iron-sulfur cluster assembly enzyme ISCU, mitochondrial, anticorps iron-sulfur cluster assembly enzyme, anticorps iron-sulfur cluster assembly enzyme a, anticorps LOC409130, anticorps ISCU, anticorps iscua, anticorps Iscu
- Sujet
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Background: Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins (PubMed:11060020). First, a [2Fe-2S] cluster is transiently assembled on the scaffold protein ISCU. In a second step, the cluster is released from ISCU, transferred to a glutaredoxin GLRX5, followed by the formation of mitochondrial [2Fe-2S] proteins, the synthesis of [4Fe-4S] clusters and their target-specific insertion into the recipient apoproteins. Cluster assembly on ISCU depends on the function of the cysteine desulfurase complex NFS1-LYRM4/ISD11, which serves as the sulfur donor for cluster synthesis, the iron-binding protein frataxin as the putative iron donor, and the electron transfer chain comprised of ferredoxin reductase and ferredoxin, which receive their electrons from NADH (By similarity).
Aliases: 2310020H20Rik antibody, HML antibody, hnifU antibody, Iron sulfur cluster assembly enzyme ISCU mitochondrial antibody, Iron sulfur cluster scaffold homolog (E. coli) antibody, Iron sulfur cluster scaffold homolog antibody, Iron-sulfur cluster assembly enzyme ISCU antibody, Iscu antibody, IscU iron sulfur cluster scaffold homolog antibody, ISCU_HUMAN antibody, ISU2 antibody, MGC74517 antibody, mitochondrial antibody, NIFU antibody, NifU like N terminal domain containing antibody, NifU like N terminal domain containing protein antibody, NifU like protein antibody, NifU-like N-terminal domain-containing protein antibody, NifU-like protein antibody, NIFUN antibody, Nitrogen fixation cluster like antibody, OTTHUMP00000238760 antibody, OTTHUMP00000238761 antibody, OTTHUMP00000238762 antibody, OTTHUMP00000238764 antibody, OTTHUMP00000238765 antibody
- UniProt
- Q9H1K1
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