JUP anticorps (AA 1-131)

N° du produit ABIN7157158

Détail du produit anti-JUP anticorps

Antigène: JUP (Junction Plakoglobin (JUP))

Épitope: AA 1-131

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp JUP est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Junction plakoglobin protein (1-131AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur JUP

Antigène: JUP (Junction Plakoglobin (JUP))

Autre désignation: JUP (JUP Produits)

Synonymes: anticorps ARVD12, anticorps CTNNG, anticorps DP3, anticorps DPIII, anticorps PDGB, anticorps PKGB, anticorps arvd12, anticorps ctnng, anticorps dp3, anticorps dpiii, anticorps pdgb, anticorps pkgb, anticorps plak, anticorps D930025P04Rik, anticorps PG, anticorps cb80, anticorps danPG, anticorps fb11b06, anticorps jup, anticorps wu:fb11b06, anticorps junction plakoglobin, anticorps junction plakoglobin L homeolog, anticorps Junction plakoglobin, anticorps junction plakoglobin a, anticorps junction plakoglobin S homeolog, anticorps JUP, anticorps Jup, anticorps jup, anticorps jup.L, anticorps Tsp_06656, anticorps plak, anticorps jupa, anticorps jup.S

Sujet:

Background: Common junctional plaque protein. The membrane-associated plaques are architectural elements in an important strategic position to influence the arrangement and function of both the cytoskeleton and the cells within the tissue. The presence of plakoglobin in both the desmosomes and in the intermediate junctions suggests that it plays a central role in the structure and function of submembranous plaques. Acts as a substrate for VE-PTP and is required by it to stimulate VE-cadherin function in endothelial cells. Can replace beta-catenin in E-cadherin/catenin adhesion complexes which are proposed to couple cadherins to the actin cytoskeleton (By similarity).

Aliases: ARVD 12 antibody, ARVD12 antibody, Catenin (cadherin associated protein), gamma 80 kDa antibody, catenin (cadherin-associated protein) gamma (80kD) antibody, Catenin gamma antibody, CTNNG antibody, Desmoplakin 3 antibody, Desmoplakin III antibody, Desmoplakin-3 antibody, Desmoplakin3 antibody, DesmoplakinIII antibody, DP 3 antibody, DP III antibody, DP3 antibody, DPIII antibody, gamma catenin antibody, Junction plakoglobin antibody, JUP antibody, OTTHUMP00000164732 antibody, OTTHUMP00000164735 antibody, OTTHUMP00000164738 antibody, PDGB antibody, PKGB antibody, PLAK_HUMAN antibody, PLAKOGLOBIN antibody

UniProt: P14923

Pathways: Cell-Cell Junction Organization, Maintenance of Protein Location