KLHL22 anticorps (AA 2-300)

N° du produit ABIN7157281

Détail du produit anti-KLHL22 anticorps

Antigène: KLHL22 (Kelch-Like 22 (KLHL22))

Épitope: AA 2-300

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KLHL22 est non-conjugé

Application: Western Blotting (WB), ELISA

Réactivité croisée: Humain, Souris

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Kelch-like protein 22 protein (2-300AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:500-1:2000,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur KLHL22

Antigène: KLHL22 (Kelch-Like 22 (KLHL22))

Autre désignation: KLHL22 (KLHL22 Produits)

Synonymes: anticorps 2610318I18Rik, anticorps Kelchl, anticorps KELCHL, anticorps RGD1306288, anticorps kelch-like 22, anticorps kelch like family member 22, anticorps kelch-like family member 22, anticorps Klhl22, anticorps KLHL22

Sujet:

Background: Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex required for chromosome alignment and localization of PLK1 at kinetochores. The BCR(KLHL22) ubiquitin ligase complex mediates monoubiquitination of PLK1, leading to PLK1 dissociation from phosphoreceptor proteins and subsequent removal from kinetochores, allowing silencing of the spindle assembly checkpoint (SAC) and chromosome segregation. Monoubiquitination of PLK1 does not lead to PLK1 degradation.

Aliases: KLHL22Kelch-like protein 22 antibody

UniProt: Q53GT1