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KIF14 anticorps (AA 261-531) (Biotin)

KIF14 Reactivité: Humain ELISA Hôte: Lapin Polyclonal Biotin
N° du produit ABIN7157596
  • Antigène Voir toutes KIF14 Anticorps
    KIF14 (Kinesin Family Member 14 (KIF14))
    Épitope
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 261-531
    Reactivité
    • 23
    • 4
    • 4
    • 1
    Humain
    Hôte
    • 22
    • 1
    Lapin
    Clonalité
    • 23
    Polyclonal
    Conjugué
    • 12
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp KIF14 est conjugé à/à la Biotin
    Application
    • 12
    • 9
    • 8
    • 6
    • 6
    • 2
    • 2
    • 1
    • 1
    ELISA
     Réactivité croisée
    Humain
    Purification
    >95%, Protein G purified
    Immunogène
    Recombinant Human Kinesin-like protein KIF14 protein (261-531AA)
    Isotype
    IgG
    Top Product
    Discover our top product KIF14 Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Antigène
    KIF14 (Kinesin Family Member 14 (KIF14))
    Autre désignation
    KIF14 (KIF14 Produits)
    Synonymes
    anticorps wu:fi16h07, anticorps si:dkey-39e8.3, anticorps KIF14, anticorps D1Ertd367e, anticorps E130203M01, anticorps kinesin family member 14, anticorps kinesin-like protein KIF14, anticorps KIF14, anticorps kif14, anticorps LOC100641544, anticorps Kif14
    Sujet

    Background: Microtubule motor protein that binds to microtubules with high affinity through each tubulin heterodimer and has an ATPase activity (By similarity). Plays a role in many processes like cell division, cytokinesis and also in cell proliferation and apoptosis (PubMed:24784001, PubMed:16648480). During cytokinesis, targets to central spindle and midbody through its interaction with PRC1 and CIT respectively (PubMed:16431929). Regulates cell growth through regulation of cell cycle progression and cytokinesis (PubMed:24854087). During cell cycle progression acts through SCF-dependent proteasomal ubiquitin-dependent protein catabolic process which controls CDKN1B degradation, resulting in positive regulation of cyclins, including CCNE1, CCND1 and CCNB1 (PubMed:24854087). During late neurogenesis, regulates the cerebellar, cerebral cortex and olfactory bulb development through regulation of apoptosis, cell proliferation and cell division (By similarity). Also is required for chromosome congression and alignment during mitotic cell cycle process (PubMed:15843429). Regulates cell spreading, focal adhesion dynamics, and cell migration through its interaction with RADIL resulting in regulation of RAP1A-mediated inside-out integrin activation by tethering RADIL on microtubules (PubMed:23209302).

    Aliases: KIAA0042 antibody, KIF 14 antibody, KIF14 antibody, KIF14_HUMAN antibody, Kinesin Family Member 14 antibody, Kinesin like protein KIF14 antibody, Kinesin-like protein KIF14 antibody, MGC142302 antibody

    UniProt
    Q15058
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