KIF2B anticorps (AA 1607-1731)

N° du produit ABIN7157616

Détail du produit anti-KIF2B anticorps

Antigène: KIF2B (Kinesin Family Member 2B (KIF2B))

Épitope: AA 1607-1731

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KIF2B est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Kinesin-like protein KIF20B protein (1607-1731AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:200-1:500, IF:1:50-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur KIF2B

Antigène: KIF2B (Kinesin Family Member 2B (KIF2B))

Autre désignation: KIF2B (KIF2B Produits)

Synonymes: anticorps 1700063D03Rik, anticorps QtsA-13688, anticorps QtsA-18420, anticorps kinensin, anticorps kinesin family member 2B, anticorps Kif2b, anticorps KIF2B

Sujet:

Background: Plus-end-directed motor enzyme that is required for completion of cytokinesis (PubMed:11470801, PubMed:12740395). Required for proper midbody organization and abscission in polarized cortical stem cells. Plays a role in the regulation of neuronal polarization by mediating the transport of specific cargos. Participates in the mobilization of SHTN1 and in the accumulation of PIP3 in the growth cone of primary hippocampal neurons in a tubulin and actin-dependent manner. In the developing telencephalon, cooperates with SHTN1 to promote both the transition from the multipolar to the bipolar stage and the radial migration of cortical neurons from the ventricular zone toward the superficial layer of the neocortex. Involved in cerebral cortex growth (By similarity). Acts as an oncogene for promoting bladder cancer cells proliferation, apoptosis inhibition and carcinogenic progression (PubMed:17409436).

Aliases: Cancer/testis antigen 90 antibody, CT90 antibody, KI20B_HUMAN antibody, KIF20B antibody, Kinesin-like protein KIF20B antibody, Kinesin-related motor interacting with PIN1 antibody, KRMP1 antibody, M-phase phosphoprotein 1 antibody, MPHOSPH1 antibody, MPP 1 antibody, Mpp1 antibody

UniProt: Q96Q89

Pathways: Dynamique des Microtubules