ANKRD15 anticorps (AA 66-255)

N° du produit ABIN7157686

Détail du produit anti-ANKRD15 anticorps

Antigène: ANKRD15 (Ankyrin Repeat Domain 15 (ANKRD15))

Épitope: AA 66-255

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ANKRD15 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human KN motif and ankyrin repeat domain-containing protein 1 protein (66-255AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:200-1:500,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur ANKRD15

Antigène: ANKRD15 (Ankyrin Repeat Domain 15 (ANKRD15))

Autre désignation: KANK1 (ANKRD15 Produits)

Synonymes: anticorps ANKRD15, anticorps CPSQ2, anticorps KANK, anticorps A930031B09Rik, anticorps AU015049, anticorps AW121052, anticorps Ankrd15, anticorps D330024H06Rik, anticorps mKIAA0172, anticorps KANK1, anticorps ankrd15, anticorps kank1.2, anticorps DMRT1, anticorps KN motif and ankyrin repeat domains 1, anticorps KN motif and ankyrin repeat domains 1 L homeolog, anticorps doublesex and mab-3 related transcription factor 1, anticorps KANK1, anticorps Kank1, anticorps kank1.L, anticorps DMRT1

Sujet:

Background: Involved in the control of cytoskeleton formation by regulating actin polymerization. Inhibits actin fiber formation and cell migration. Inhibits RhoA activity, the function involves phosphorylation through PI3K/Akt signaling and may depend on the competetive interaction with 14-3-3 adapter proteins to sequester them from active complexes. Inhibits the formation of lamellipodia but not of filopodia, the function may depend on the competetive interaction with BAIAP2 to block its association with activated RAC1. Inhibits fibronectin-mediated cell spreading, the function is partially mediated by BAIAP2. Inhibits neurite outgrowth. Involved in the establishment and persistence of cell polarity during directed cell movement in wound healing. In the nucleus, is involved in beta-catenin-dependent activation of transcription. Potential tumor suppressor for renal cell carcinoma.

Aliases: ANKRD 15 antibody, Ankyrin repeat domain 15 antibody, Ankyrin repeat domain containing protein 15 antibody, Ankyrin repeat domain-containing protein 15 antibody, DKFZp451G231 antibody, KANK antibody, KANK1 antibody, KANK1_HUMAN antibody, KIAA0172 antibody, Kidney ankyrin repeat containing protein antibody, Kidney ankyrin repeat-containing protein antibody, KN motif and ankyrin repeat domain-containing protein 1 antibody, MGC43128 antibody

UniProt: Q14678

Pathways: Regulation of Actin Filament Polymerization