KANK2 anticorps (AA 410-585) (Biotin)

N° du produit ABIN7157691

Détail du produit anti-KANK2 anticorps (Biotin)

Antigène: KANK2 (KN Motif and Ankyrin Repeat Domains 2 (KANK2))

Épitope: AA 410-585

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KANK2 est conjugé à/à la Biotin

Application: ELISA

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human KN motif and ankyrin repeat domain-containing protein 2 protein (410-585AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur KANK2

Antigène: KANK2 (KN Motif and Ankyrin Repeat Domains 2 (KANK2))

Autre désignation: KANK2 (KANK2 Produits)

Synonymes: anticorps ANKRD25, anticorps MXRA3, anticorps SIP, anticorps AI504612, anticorps Ankrd25, anticorps BC010245, anticorps KN motif and ankyrin repeat domains 2, anticorps KANK2, anticorps Kank2

Sujet:

Background: Involved in transcription regulation by sequestering nuclear receptor coactivators, such as NCOA1, NCOA2 and NCOA3, in the cytoplasm, the function is deregulated by phosphorylation. Involved in the negative control of vitamin D receptor signaling pathway (PubMed:24671081). May be involved in the control of cytoskeleton formation by regulating actin polymerization. Involved in regulation of caspase-independent apoptosis, proposed to sequester AIFM1 in mitochondria and apoptotic stimuli lead to its proteasomal degradation allowing the release of AIFM1 to the nucleus (PubMed:22371500). May be involved in promotion of cell proliferation (By similarity).

Aliases: KANK2 antibody, ANKRD25 antibody, KIAA1518 antibody, MXRA3 antibody, SIP antibody, KN motif and ankyrin repeat domain-containing protein 2 antibody, Ankyrin repeat domain-containing protein 25 antibody, Matrix-remodeling-associated protein 3 antibody, SRC-1-interacting protein antibody, SIP antibody, SRC-interacting protein antibody, SRC1-interacting protein antibody

UniProt: Q63ZY3