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KLF1 anticorps (AA 1-362) (HRP)

KLF1 Reactivité: Humain ELISA Hôte: Lapin Polyclonal HRP
N° du produit ABIN7157706
  • Antigène Voir toutes KLF1 Anticorps
    KLF1 (Kruppel-Like Factor 1 (erythroid) (KLF1))
    Épitope
    • 9
    • 9
    • 6
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-362
    Reactivité
    • 45
    • 5
    • 5
    • 4
    • 4
    • 4
    • 2
    Humain
    Hôte
    • 34
    • 11
    • 1
    Lapin
    Clonalité
    • 36
    • 11
    Polyclonal
    Conjugué
    • 27
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp KLF1 est conjugé à/à la HRP
    Application
    • 32
    • 26
    • 3
    • 3
    • 1
    ELISA
     Réactivité croisée
    Humain
    Purification
    >95%, Protein G purified
    Immunogène
    Recombinant Human Krueppel-like factor 1 protein (1-362AA)
    Isotype
    IgG
    Top Product
    Discover our top product KLF1 Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Antigène
    KLF1 (Kruppel-Like Factor 1 (erythroid) (KLF1))
    Autre désignation
    KLF1 (KLF1 Produits)
    Synonymes
    anticorps KLF1, anticorps EKLF, anticorps HBFQTL6, anticorps INLU, anticorps Eklf, anticorps Nan, anticorps Kruppel-like factor 1 (erythroid), anticorps Kruppel like factor 1, anticorps KLF-4, anticorps KLF1, anticorps Klf1
    Sujet

    Background: Transcription regulator of erythrocyte development that probably serves as a general switch factor during erythropoiesis. Is a dual regulator of fetal-to-adult globin switching. Binds to the CACCC box in the beta-globin gene promoter and acts as a preferential activator of this gene. Furthermore, it binds to the BCL11A promoter and activates expression of BCL11A, which in turn represses the HBG1 and HBG2 genes. This dual activity ensures that, in most adults, fetal hemoglobin levels are low. Able to activate CD44 and AQP1 promoters. When sumoylated, acts as a transcriptional repressor by promoting interaction with CDH2/MI2beta and also represses megakaryocytic differentiation.

    Aliases: CDAN4 antibody, EKLF antibody, EKLF PEN antibody, Erythroid krueppel like transcription factor (EKLF) (Erythroid transcription factor) antibody, Erythroid krueppel-like transcription factor antibody, Erythroid Kruppel like factor antibody, Erythroid specific transcription factor EKLF antibody, HBFQTL6 antibody, Human erythroid-specific transcription factor EKLF mRNA complete cds antibody, INLU antibody, Klf1 antibody, KLF1_HUMAN antibody, Krueppel-like factor 1 antibody, Kruppel like factor 1 (erythroid) antibody

    UniProt
    Q13351
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