LDLRAP1 anticorps (AA 59-308)
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- Antigène Voir toutes LDLRAP1 Anticorps
- LDLRAP1 (Low Density Lipoprotein Receptor Adaptor Protein 1 (LDLRAP1))
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Épitope
- AA 59-308
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp LDLRAP1 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA
- Réactivité croisée
- Humain, Souris
- Purification
- Antigen Affinity Purified
- Immunogène
- Recombinant Human Low density lipoprotein receptor adapter protein 1 protein (59-308AA)
- Isotype
- IgG
- Top Product
- Discover our top product LDLRAP1 Anticorps primaire
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- Indications d'application
- Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Antigène
- LDLRAP1 (Low Density Lipoprotein Receptor Adaptor Protein 1 (LDLRAP1))
- Autre désignation
- LDLRAP1 (LDLRAP1 Produits)
- Synonymes
- anticorps ARH, anticorps ARH1, anticorps ARH2, anticorps FHCB1, anticorps FHCB2, anticorps AA691260, anticorps Arh, anticorps Arh1, anticorps RGD1563417, anticorps arh, anticorps arh1, anticorps arh2, anticorps fhcb1, anticorps fhcb2, anticorps xptb, anticorps LDLRAP1, anticorps ldlrap1, anticorps sb:cb50, anticorps zgc:56121, anticorps zgc:158745, anticorps low density lipoprotein receptor adaptor protein 1, anticorps low density lipoprotein receptor adaptor protein 1 L homeolog, anticorps low density lipoprotein receptor adaptor protein 1 S homeolog, anticorps low density lipoprotein receptor adaptor protein 1a, anticorps low density lipoprotein receptor adaptor protein 1b, anticorps LDLRAP1, anticorps Ldlrap1, anticorps ldlrap1, anticorps ldlrap1.L, anticorps ldlrap1.S, anticorps ldlrap1a, anticorps ldlrap1b
- Sujet
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Background: Adapter protein (clathrin-associated sorting protein (CLASP)) required for efficient endocytosis of the LDL receptor (LDLR) in polarized cells such as hepatocytes and lymphocytes, but not in non-polarized cells (fibroblasts). May be required for LDL binding and internalization but not for receptor clustering in coated pits. May facilitate the endocytocis of LDLR and LDLR-LDL complexes from coated pits by stabilizing the interaction between the receptor and the structural components of the pits. May also be involved in the internalization of other LDLR family members. Binds to phosphoinositides, which regulate clathrin bud assembly at the cell surface.
Aliases: ARH antibody, ARH GENE antibody, ARH_HUMAN antibody, ARH1 antibody, ARH2 antibody, Autosomal recessive hypercholesterolemia protein antibody, DKFZp586D0624 antibody, FHCB1 antibody, FHCB2 antibody, LDL receptor adaptor protein antibody, Ldlrap1 antibody, Low density lipoprotein receptor adapter protein 1 antibody, MGC34705 antibody, OTTHUMP00000008526 antibody
- UniProt
- Q5SW96
- Pathways
- Lipid Metabolism
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