KDM4A anticorps (AA 127-364) (HRP)

N° du produit ABIN7158698

Détail du produit anti-KDM4A anticorps (HRP)

Antigène: KDM4A (Lysine (K)-Specific Demethylase 4A (KDM4A))

Épitope: AA 127-364

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KDM4A est conjugé à/à la HRP

Application: ELISA

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Lysine-specific demethylase 4A protein (127-364AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur KDM4A

Antigène: KDM4A (Lysine (K)-Specific Demethylase 4A (KDM4A))

Autre désignation: KDM4A (KDM4A Produits)

Sujet:

Background: Histone demethylase that specifically demethylates \'Lys-9\' and \'Lys-36\' residues of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 \'Lys-4\', H3 \'Lys-27\' nor H4 \'Lys-20\'. Demethylates trimethylated H3 \'Lys-9\' and H3 \'Lys-36\' residue, while it has no activity on mono- and dimethylated residues. Demethylation of Lys residue generates formaldehyde and succinate. Participates in transcriptional repression of ASCL2 and E2F-responsive promoters via the recruitment of histone deacetylases and NCOR1, respectively.

Aliases: JHDM3A antibody, JmjC domain containing histone demethylation protein 3A antibody, JmjC domain-containing histone demethylation protein 3A antibody, JMJD2 antibody, JMJD2A antibody, jumonji C domain containing histone demethylase 3A antibody, Jumonji domain containing 2 antibody, Jumonji domain containing 2A antibody, Jumonji domain containing protein 2A antibody, Jumonji domain-containing protein 2A antibody, KDM4A antibody, KDM4A_HUMAN antibody, KIAA0677 antibody, Lysine (K) specific demethylase 4A antibody, Lysine-specific demethylase 4A antibody, TDRD14A antibody, Tudor domain containing 14A antibody

UniProt: O75164

Pathways: L'effet Warburg